objective: today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-zro2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. however, there are some reports implying that use of nano-zro2 is associated with cytotoxic effects like inhibiting the cell proliferation, dna damage and apoptosis. in the present study, we examined whether nano-z...

linezolid (lzd), severed as the first oxazolidinone antibiotic, was active against multidrug-resistant gram-positive strains. lzd can induce thrombocytopenia, anemia and leukocytopenia. currently, reports on pure red cell aplasia (prca) cases induced by lzd are relatively rare [4-7]. in this paper, we reported a patient with prca twice induced by lzd. a 37-year-old man was diagnosed with myelody...

background: the anticancer agent imatinib (im) is a small molecular analog ofatp that inhibits tyrosine kinase activity of platelet derived growth factors (pdgfs)and stem cell factor (scf) receptor in cancer cells. however these factors have a keyrole in regulating growth and development of normal sertoli, leydig and germcells.objective: the aim of this study was to determine cell viability, pd...

acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. the conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. it has been rarely reported in the literature. in leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. herein, we rep...

ten cases of synovial cell sarcoma are reported. the youngest patient was a 2'a years old boy with synovial cell sarcoma of the knee and the oldest one was a man with synovial cell sarcoma of the elbow.

background & objectives: chronicity of lupus nephritis (ln) should be considered for interaction of cell mediated immunity (cmi) and dendritic cells in glomeruli and tubulointerstitial areas. in this study establishment of immunohistopathological changes of dendritic cells and other immune effector cells in lupus nephritis comparing with non-lupus nephritis was performed. materials & m...

giant cell carcinoma of the endometrium is a rare and an aggressive tumor that should be distinguished from other endometrial tumors with a prominent giant cell component, including trophoblastic tumors, certain primary sarcomas, and malignant mixed müllerian tumors. at present, cumulative data on this rare histological variant is limited and the prognostic significance of the presence and the ...

background: a lot of investigations exist on the biological effects of radiofrequency and microwave radiation however only a few studies have considered non-carcinogenic exposure to radiations specifically from mobile phones. objectives: to introduce some subjective neurological symptoms in mobile phone users. materials and methods: in this cross-sectional descriptive study conducted from march...

testicular germ-cell tumors are the most common malignancy among men aged 20-40 years, and 60 percent of them are seminomas. these tumors are now an important socio-economic problem, considering their growing incidence. thus we undertook to evaluate the results of curative irradiation in our testicular seminoma patients and compare them to literature results considering the use of cobalt-60 sys...