Physiological and biochemical studies were carried out on 16 patients with motor neurone disease (MND). It was confirmed that the peripheral nerves in cases of MND are often unusually resistant to ischaemia especially as regards the large sensory fibres. Biochemical investigations demonstrated a tendency to carbohydrate intolerance and abnormal pyruvate metabolism. When compared with other rela...

Background: Majority of Burkinabè adults were normal-weight by body mass index (BMI). This study explored gender, the metabolic abnormalities and “metabolic obesity with weight” (MONW) throughout normal BMI quartiles (Q) adults. Methods: We performed a secondary-analysis data from first WHO Stepwise approach to surveillance survey conducted in 2013 Burkina Faso, only between 18.5 ...

Abstract Absences pose a dilemma for theories of causation. Allowing them to be causes seems make too permissive. Banning from being restrictive. An increasingly popular approach this is acknowledge that norms can affect which absences count as causes. In article, I distinguish between two influential implementations such ‘abnormality’ approaches and argue so-called ‘double-prevention mechanism...

Metabolic epilepsy is a metabolic abnormality which is associated with an increased risk of epilepsy development in affected individuals. Commonly used antiepileptic drugs are typically ineffective against metabolic epilepsy as they do not address its root cause. Presently, there is no review available which summarizes all the treatment options for metabolic epilepsy. Thus, we systematically re...

PURPOSE OF REVIEW Oxidative stress describes an imbalance between production and degradation of reactive oxygen species (ROS), which can damage macromolecules. However, ROS may also serve as signaling molecules activating cellular pathways involved in cell proliferation and adaptation. This review describes alterations in metabolic diseases including obesity, insulin resistance, and/or diabetes...

Seventy four patients (66 men, eight women; mean age 54.3 years) underwent submaximal exercise testing 7-23 days (mean 10.7) after acute myocardial infarction. Follow up was a mean period of 11.3 months. When compared with patients with no exercise induced abnormality, ST segment elevation, ST shift (depression or elevation or both), ST depression, inability to complete five metabolic equivalen...

Centropontine myelinolysis (MCP) belongs to the osmotic demyelination syndrome, and occurs especially after rapid correction of hyponatremia. In rare cases, it is caused by states hyperosmolarity can be seen in hyperglycemia. Here, we report case a 28-year-old diabetic patient, admitted intensive care unit for disorder consciousness seizures. The physical examination found an apyretic patient w...