Sodium-glucose co-transporter-2 (SGLT2) inhibitors are well-recognised antidiabetic medications among clinicians due to its highly protective effects on cardiovascular and renal systems diabetic patients. However, one of uncommonly reported side is the development euglycemic ketoacidosis (EuDKA) which characterized by mild hyperglycemia, ketosis acidosis. Chest pain as a clinical present...

Thioredoxin reductase (TrxR) is an enzyme that involved in many metabolic pathways from detoxification to reduction of radicals by catalyzing the thioredoxin, and therefore associated with physiological processes, including cancer. Inhibitors this are considered anticancer targets. In past studies, some antidepressants have been found effects through various mechanisms, reuse as drugs has attra...