BACKGROUND Insulin resistance is accompanied by a cluster of metabolic changes, often referred to as metabolic syndrome. Metabolic syndrome is associated with an increased cardiovascular risk in patients with manifest arterial disease. We investigated whether insulin resistance is associated with an increased risk for cardiovascular events in patients with manifest arterial disease without know...

BACKGROUND Metabolic syndrome is known to be a prothrombotic state. We undertook this study to examine a hypothesis that aspirin resistance may be associated with metabolic syndrome, and to assess other potential determinants of aspirin resistance in patients with cardiovascular disease (CVD). METHODS A total of 469 elderly patients with CVD were recruited. One hundred and seventy-two patient...

The metabolic syndrome affects more than a third of the US and Mexican populations, predisposing to the development of some metabolic disorders.1,2 In fact, it is well recognized that subjects with generalized obesity suffer from a high risk of insulin resistance and its metabolic complications, such as type 2 diabetes mellitus, hypertriglyceridemia, low levels of high density lipoprotein chole...

BACKGROUND AND OBJECTIVES The metabolic syndrome is associated with alterations in renal function. An overly acidic urine has been described as a renal manifestation of the metabolic syndrome in patients with kidney stone disease. This study examined the association between the metabolic syndrome and urine pH in individuals without a history of nephrolithiasis. DESIGN, SETTING, PARTICIPANTS, ...

OBJECTIVE — Metabolic syndrome is a cluster of risk factors for cardiovascular disease and type 2 diabetes. Definitions exist to identify those “at risk.” Treatment of HIV infection with highly active antiretroviral therapy can induce severe metabolic complications including lipodystrophy, dyslipidemia, and insulin resistance. The purpose of this study was to report the prevalence of metabolic ...

Glucose Homeostasis and the Metabolic Syndrome Glucose homeostasis represents the outcome of a complex feedback system for maintaining glucose tolerance within rather narrow physiological limits. Aberrant glucose homeostasis contributes to a number of downstream effects, including insulin resistance. Insulin resistance occurs when muscle, fat, or liver does not appropriately use the insulin tha...

Diabetes mellitus is a group of metabolic diseases. Insulin resistance is defined as a state that needs more insulin to get the biological effects achieved by a lower amount of insulin in the normal state. Several molecules which are secreted through adipocytes have been involved in insulin resistance and type 2 diabetes mellitus. Adiponectin as a 244 amino acid protein is exclusively expressed...

Glucose Homeostasis and the Metabolic Syndrome Glucose homeostasis represents the outcome of a complex feedback system for maintaining glucose tolerance within rather narrow physiological limits. Aberrant glucose homeostasis contributes to a number of downstream effects, including insulin resistance. Insulin resistance occurs when muscle, fat, or liver does not appropriately use the insulin tha...