نتایج جستجو برای: metabolic tumor volume

تعداد نتایج: 932681  

Journal: :iranian journal of pharmaceutical research 0
maryam nakhjavani department of pharmaco/toxicology, school of pharmacy, shahid beheshti medical university, tehran, iran. nastaran nikounezhad department of pharmaco/toxicology, school of pharmacy, shahid beheshti medical university, tehran, iran. azadeh ashtarinezhad department of occupational hygiene, school of hygiene, iran university of medical sciences, tehran, iran. occupational health research center, school of public health, iran university of medical sciences, tehran, iran. farshad h shirazi department of pharmaco/toxicology, school of pharmacy, shahid beheshti medical university, tehran, iran. pharmaceutical sciences research center, shahid beheshti medical university, tehran, iran.

cancer treatment is still of the greatest challenges that health care providers and patients are facing. one of the unsolved problems in cancer treatment is cells’ reaction to metabolic stress caused by harsh nutritional conditions around tumor. in order to be able to treat this disease properly, it is important to understand the true nature of the disease. in fact, the cells inside the central...

2015
Mau-Shin Chi Cheng-Yen Lee Su-Chen Huang Kai-Lin Yang Hui-Ling Ko Yen-Kung Chen Chen-Han Chung Kuang-Wen Liao Kwan-Hwa Chi

RATIONALE According to the metabolic symbiosis model, cancer stromal fibroblasts could be hijacked by surrounding cancer cells into a state of autophagy with aerobic glycolysis to help provide recycled nutrients. The purpose of this study was to investigate whether combined treatment with the autophagy inhibitor: hydroxychloroquine (HCQ) and the autophagy inducer: sirolimus (rapamycin, Rapa) wo...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Olivier Keunen Mikael Johansson Anaïs Oudin Morgane Sanzey Siti A Abdul Rahim Fred Fack Frits Thorsen Torfinn Taxt Michal Bartos Radovan Jirik Hrvoje Miletic Jian Wang Daniel Stieber Linda Stuhr Ingrid Moen Cecilie Brekke Rygh Rolf Bjerkvig Simone P Niclou

Bevacizumab, an antibody against vascular endothelial growth factor (VEGF), is a promising, yet controversial, drug in human glioblastoma treatment (GBM). Its effects on tumor burden, recurrence, and vascular physiology are unclear. We therefore determined the tumor response to bevacizumab at the phenotypic, physiological, and molecular level in a clinically relevant intracranial GBM xenograft ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Catharina M L Zegers Wouter van Elmpt Bart Reymen Aniek J G Even Esther G C Troost Michel C Ollers Frank J P Hoebers Ruud M A Houben Jonas Eriksson Albert D Windhorst Felix M Mottaghy Dirk De Ruysscher Philippe Lambin

PURPOSE Increased tumor metabolism and hypoxia are related to poor prognosis in solid tumors, including non-small cell lung cancer (NSCLC). PET imaging is a noninvasive technique that is frequently used to visualize and quantify tumor metabolism and hypoxia. The aim of this study was to perform an extensive comparison of tumor metabolism using 2[(18)F]fluoro-2-deoxy-d-glucose (FDG)-PET and hypo...

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