Objectives: Methamphetamine (MA) dependence is a new health problem among Iranian female methadone patients. In recent years, the Matrix Model (a sixteen-week psychosocial treatment) has been provided for treating MA dependence. However, the problems associated with this treatment in methadone services are not clear. Methods: A qualitative study was conducted to explore the problems associated...

Progress in understanding the neurobiology of stimulant dependence has enabled researchers to identify medications whose pharmacological effects suggest that they might help patients initiate abstinence or avoid relapse. Several of these medications and a vaccine have shown encouraging results in controlled clinical trials with cocaine-dependent patients. The search for a medical treatment for ...

Primary care physicians treating HIV-infected patients should not be afraid or reluctant to engage in medication-assisted treatment for substance dependence. Effective medications are available for many types of substance addictions, including buprenorphine for opioid dependence, disulfiram for cocaine dependence, bupropion for methamphetamine dependence, and naltrexone for alcohol dependence. ...

OBJECTIVES This study evaluated the effect of swimming exercise during spontaneous methamphetamine (METH) withdrawal on the anxiety, depression, obsessive-compulsive disorder (OCD) and voluntary METH consumption in METH-dependent rats. MATERIALS AND METHODS Male Wistar rats were repeatedly administered with bi-daily doses of METH (2 mg/kg, subcutaneous) over a period of 14 days. Exercised rat...

BACKGROUND The abuse of narcotic drugs and psychotropic substances such as amphetamines and ecstasy has had a growing trend. Tachycardia, increased blood pressure, hallucinations, panic attacks, and psychosis are the negative effects of methamphetamine abuse. The present study aimed to assess psychiatric disorders associated with methamphetamine-induced psychotic disorder. METHODS This cross-...

background previous studies have proven the development of white matter hyperintensities (wmh) in methamphetamine and opioid users. opiates and methamphetamines (ma) are the most common addictive agents in iran. the adverse effects of drugs on the cns is of concern to specialists and researchers, and given that the neurotoxicity associated with methamphetamine is greater than opioids, it is hyp...

We examined human immunodeficiency virus (HIV)-related risk behaviors among methamphetamine (MA)-dependent users. Secondary data analysis was performed on data from a large clinical trial: The Methamphetamine Treatment Project (N = 784). All MA-dependent participants were enrolled in an outpatient treatment program, receiving either a standardized psychosocial protocol (Matrix model) or treatme...