b ackground: methicillin-resistant staphylococcus aureus (mrsa) is the one of most commonly isolated organisms from clinical samples which can cause life- threatening infections. the emergence and spread of antibiotic resistance makes the treatment of these infections more complicated. in this study, we aimed to determine  the  patterns  of  antibiotic  resistance  among  mrsa  isolates  from t...

background: staphylococcus aureus has been recognized as a major human pathogen and is the major cause of nosocomial infections. gamma-toxin, leukocidin and other bi-component toxins are a family of proteins encoded by the hlg and luk-pv, respectively. panton-valentine leukocidin (pvl) is an example of these toxins and causes leukocyte destruction and tissue necrosis. the aim of this study was ...

background methicillin-resistant staphylococcus aureus (mrsa) remains a significant public health problem and treatment challenge. objectives this study was conducted to determine the frequency, molecular types, and drug resistance of s. aureus isolated from nasal carriers in two teaching hospitals (hajar and kashani) in shahrekord, southwestern iran. methods in this cross-sectional study, 262 ...

conclusions regarding clinical and laboratory standards institute (clsi) definition for vancomycin susceptibility (mic < 2 μg/ml), it seems that vancomycin may not be considered as the best antibiotic in order to treat heteroresistant vancomycin intermediate s. aureus (hvisa) and vancomycin sensitive s. aureus (vssa) infections, and a new breakpoint for vancomycin and alternative antibiotics sh...

Mupirocin MICs and mupA presence were determined in 108 staphylococci causing prosthetic joint infection. Zero of 35 isolates (0%) of methicillin-susceptible Staphylococcus aureus, 4/15 (27%) methicillin-resistant S. aureus isolates, 3/16 (19%) methicillin-susceptible coagulase-negative staphylococci, and 11/42 (26%) methicillin-resistant coagulase-negative staphylococci were mupirocin resistan...

Methicillin Resistant Staphylococcus aureus (MRSA) has been recently growing problem in small animal clinical practice due to increasing resistance to multiple number of antimicrobials. Present study reports about the antimicrobial susceptibility pattern of MRSA isolated from the dogs with recurrent pyoderma. Based on the cultural and biochemical studies 12 isolates were identified as Staphyloc...

Mupirocin is a topical antimicrobial agent utilized in treatment of methicillin resistant Staphylococcus aureus. Mupirocin resistance in Staphylococcus aureus is increasingly being reported in many parts of the world in the context of its widespread use. The objectives of this study were to determine the susceptibility of methicillin resistant Staphylococcus aureus clinical isolates to mupiroci...

Objective: We investigated the clinical characteristics, treatment patterns and outcomes of community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) septic arthritis. Methods: This was a retrospective chart review of CA-MRSA septic arthritis in a tertiary care hospital from 2000-2013. We compared CA-MRSA septic arthritis cases with HA-MRSA septic arthritis cases to identify impo...

Staphylococcus aureus infection remains an increasing problem of hospital acquired infections in burn patients, among them methicillin resistant Staphylococcus aureus poses potential cause of morbidity and mortality. Our study was carried out at the Department of Microbilogy at GMC Latur, India. From Jan 2012 to June 2013, to determine the profile of aerobic bacterial infection in burn patients...

OBJECTIVES Bactericidal activity depends on antibiotic-bacteria couples, resistance phenotype and theoretically on protein binding. This work explores the influence of protein binding on the bactericidal activity of two antibiotics, daptomycin versus vancomycin, that exhibit, respectively, different C(max) (56 versus 25.5 mg/L), protein binding (91.7% versus 36.9%) and thus theoretical free-dru...