Background: Expressed sequence tags (ESTs) are sequences of cDNA fragments prepared from different tissue sources. There are over one million of these sequences in the publicly available database, and these sequences are believed to represent more than half of all human genes. The ESTs belong to different cDNA libraries, was prepared from one particular cell type, organ, or tumor. Therefore, th...

objective: bone marrow mesenchymal stem cells reside in bone marrow and support homing and differentiation of hematopoietic stem cells (1). this makes them an excellent instrument for regenerative treatment and co-culture with the hsc. materials and methods: in this study, k562 cell lines were treated with butyric acid(for erythroid differentiation), co-cultured with mesenchymal stem cells and ...

In this paper we investigated the effect of some phytohormones on the production of flavonoids in cell suspension cultures of Digitalis lanata. There were used two cell lines and different combinations and concentrations of phytohormones. The highest flavonoids amounts were obtained after 14 days of treatment. Among the tested combinations, the highest yield of flavonoids, 7.58 mg/g d.w. (dry w...

many medical properties including antimicrobial, anticancer, antioxidant, anti-inflammatory, etc. have been mentioned for Viola odorata. results have shown the solid cell-killing effects of Viola odorata cycloidal compounds. In addition, Pathogen resistance has necessitated the study of new antimicrobial compounds. This study aimed to evaluate the antimicrobial and anticancer effects of aqueous...

PURPOSE The normal metabolite methylglyoxal (MG) specifically kills cancer cells by inhibiting glycolysis and mitochondrial respiration without much adverse effect upon normal cells. Though the anticancer property of MG is well documented, its gradual enzymatic degradation in vivo has prompted interest in developing a nanoparticulate drug delivery system to protect it and also to enhance its ef...

background: it was shown that olive leave extract has antifungal, antibacterial and antiviral activities. the effects of ole on herpes simplex virus-1 (hsv-1) have not been systematically investigated yet. the aim of this study was to examine the in vitro effect of olive leaf hydroalcoholic extract (olhe) on hsv-1.   methods: virucidal effect and viral replication in vero cell line were studied...