Antiphospholipid antibodies (aPL) have been associated with various neurological manifestations, but the underlying mechanism has not been elucidated. We assessed mice with induced experimental antiphospholipid syndrome (APS) for neurological and behavioral changes. After immunization with monoclonal human anticardiolipin antibody (H-3), female BALB/c mice developed elevated levels of circulati...

disodium hemiphthalate glycyrrhetinic acid (dhga) possesses anti-inflammatory and analgestic activities. in our research, this agent was injected intraperitoneally to mice, according to the following schedule.1) 25 mg/kg, 50mg/kg & 75mg/kg at 7th day of pregnancy.2) 50 mg/kg & 75mg/kg at 8th day of pregnancy.3) 50mg/kg & 75mg/kg at 9th day of pregnancy.dhga with doses of 50mg/kg and 75mg/kg at ...

1. The table below reports from a developmental toxicity study involving ordinal categorical outcomes. This study administered diethylene glycol dimethyl ether (an industrial solvent used in the manufacture of protective coatings) to pregnant mice. Each mouse ws exposed to one of five concentration levels for ten days early in the pregnancy (with concentration 0 corresponding to controls). Two ...

background: silymarin is a flavonolignan that has been the subject of research to evaluate the beneficial properties for decades. silymarin has been known for its potent cytoprotective, hepatoprotective and antioxidant activities. the goal of the present study was to gain a deeper understanding of possible molecular mechanisms of apoptosis of the injuries induced by silymarin on balb/c mice fet...

background: several studies have assessed the correlation of fetal choroid plexus cyst (cpc) and the risk of congenital anomalies, but few ones have discussed isolated cpc (with no other abnormal sonographic finding). objective: the aim of this study was to determine the outcome of isolated fetal choroid plexus cyst and to specify its clinical significance. materials and methods: this cross sec...

Campylobacter fetus currently comprises three recognized subspecies, which display distinct host association. Campylobacter fetus subsp. fetus and C fetus subsp. venerealis are both associated with endothermic mammals, primarily ruminants, whereas C fetus subsp. testudinum is primarily associated with ectothermic reptiles. Both C. fetus subsp. testudinum and C. fetus subsp. fetus have been asso...