BACKGROUND Two endophenotypes of arterial calcification, calcification on arterial wall and calcification in atherosclerotic plaques, are associated with different types of cardiovascular events. Mgp-deficient mice showed matrix Gla protein (MGP) is strongly associated with calcification on arterial wall without atherosclerotic plaques, and MGP variants were not significantly associated with my...

first cousin parents with two children with microcephaly and periventricular calcification were referred to our genetic counseling center. no other particular dysmorphic features were seen. intrauterine cmv infection was considered for the first child. however, the condition recurred in the second child. in this report, the importance of congenital cmv infection and its differentiation from mic...

BACKGROUND Calcification can be detected in both benign and malignant nodules and is often neglected by clinical physicians. The purpose of this study was to investigate the association of thyroid nodule calcification detected on ultrasound with thyroid carcinoma. METHODS One hundred seven cases of thyroid carcinoma and 215 cases of benign thyroid nodules were selected from the records of inp...

BACKGROUND Mitral valve calcification is often incidentally detected on chest computed tomography (CT) scans obtained for a variety of noncardiac indications. In this study, we evaluated the association between mitral valve calcification incidentally detected on chest CT and the presence and severity of mitral valve disease on echocardiography. METHODS Of 760 patients undergoing 64-row multid...

The present studies show for the first time that demineralized bone re-calcifies rapidly when incubated at 37 °C in rat serum: re-calcification can be demonstrated by Alizarin Red and von Kossa stains, by depletion of serum calcium, and by uptake of calcium and phosphate by bone matrix. Re-calcification is specific for the type I collagen matrix structures that were calcified in the original bo...

introdouction:the styloid process(sp) has the potential for calcification and ossification. the aim of this study was to investigate the prevalence of different patterns of elongation and calcification of the sp. materials and methods: in this cross-sectional study, 400 digital panoramic radiographs taken for routine dental examination in the dental school of shiraz university were evaluated fo...

conclusion statistical analysis of susceptibilities of ms patients versus healthy subjects found no excess deposition of calcium content in deep gray matter of ms patients. calcification may not be considered as a biomarker of prognosis in ms. results magnetic susceptibility(x) of calcium content was assessed by number of pixels induced by gp and put in ms patients as well as healthy subjects. ...

a case of multiple pulp stones, a supernumerary tooth and a congenitally missed tooth accompanied by several developmental dental anomalies concurrently affect- ing the upper and lower anterior teeth in an iranian healthy girl is reported. devel- opmental tooth abnormalities are usually found in conjunction with certain diseases or conditions. in the present case, although the patient had consa...

Endochondral calcification involves the participation of matrix vesicles (MVs), but it remains unclear whether calcification ectopically induced by implants of demineralized bone matrix also proceeds via MVs. Ectopic bone formation was induced by implanting rat demineralized diaphyseal bone matrix into the dorsal subcutaneous tissue of Wistar rats and was examined histologically and biochemical...

Valve interstitial cells populate aortic valve cusps and have been implicated in aortic valve calcification. Here we investigate a common in vitro model for aortic valve calcification by characterizing nodule formation in porcine aortic valve interstitial cells (PAVICs) cultured in osteogenic (OST) medium supplemented with transforming growth factor beta 1 (TGF-β1). Using a combination of mater...