In bioinformatics applications, examination of microarray data has received significant interest to diagnose diseases. Microarray gene expression can be defined by a massive searching space that poses primary challenge in the appropriate selection genes. classification incorporates multiple disciplines such as bioinformatics, machine learning (ML), science, and pattern classification. This pape...

Introduction The microarray scanner plays a pivotal role in the DNA microarray processing workflow and can profoundly affect the quality and reliability of microarray data. Since important decisions are often based on microarray scanning results, it is critical to understand the magnitude of the error contribution of each step in the microarray processing workflow compared to the total error of...

UNLABELLED The microarray gene expression markup language (MAGE-ML) is a widely used XML (eXtensible Markup Language) standard for describing and exchanging information about microarray experiments. It can describe microarray designs, microarray experiment designs, gene expression data and data analysis results. We describe RMAGEML, a new Bioconductor package that provides a link between cDNA m...

Mục tiêu: Phân tích sự thay đổi mức độ biểu hiện mRNA trên mô mỡ của gen Mest và một số liên quan đến quá trình tăng sinh ở chuột tại điều kiện khác nhau thông qua phân dữ liệu microarray. Phương pháp: Sử dụng ngôn ngữ R microarray từ bộ GSE62350 10 ngày tuổi 21 được nuôi 2 nhiệt môi trường là 17℃ 29℃ để tìm ra các có (DEG). Kết quả: Xác định 839 DEG (trong đó Mest) khi tuổi, 11 trường. Từ phát...

objective: despite the huge efforts, chronic kidney disease (ckd) remains as an unsolved problem in medicine. many studies have shown a central role for transforming growth factor beta-1 (tgfβ-1) and its downstream signaling cascades in the pathogenesis of ckd. in this study, we have reanalyzed a microarray dataset to recognize critical signaling pathways controlled by tgfβ-1. materials and met...

A new circle fitting algorithm is presented that generates the best to approximate boundary of a given microarray spot. Here, approximation means, total differential area between circumference and spot kept minimum. The center radius are determined satisfy this condition. used as quantitative metric represent quality corresponding