BACKGROUND Cerebral ischemia causes some disorders in behavioral patterns, including memory disorders and pain, which is due to the production of free radicals. Ferulago angulata, known in Iran as chavir, contains some bioactive compounds having antioxidant and free radical-scavenging properties. OBJECTIVES This study aimed to evaluate the effect of two weeks oral administration of hydroalcoh...

A number of clinical studies demonstrate that individual characteristics such as stress tolerance and cognitive ability can be considered not only diagnostic variables but also risk factors for severe cerebral hypoperfusion. The aim the study was to identify typological features effect physical activity on behavioral reactions rats during Material methods. Cerebral hypoperfusion modeled by bila...

Autism is a neurodevelopmental disorder currently affecting as many as 1 out of 166 children in the United States. Numerous studies of autistic individuals have revealed evidence of cerebral hypoperfusion, neuroinflammation and gastrointestinal inflammation, immune dysregulation, oxidative stress, relative mitochondrial dysfunction, neurotransmitter abnormalities, impaired detoxification of tox...

The Baihui acupoint has three Yang and five convergences; it is needled in order to activate spirit and resuscitate the brain in traditional Chinese medicine. Therefore, the purpose of the present study is to investigate the effect of acupuncture stimulation at the Baihui acupoint on cerebral infarct and dopamine levels. A chronic cerebral hypoperfusion animal model was established by permanent...

Limb Remote ischemic conditioning (LRIC) has been proved to be a promising neuroprotective method in white matter lesions after ischemia; however, its mechanism underlying protection after chronic cerebral hypoperfusion remains largely unknown. Here, we investigated whether LRIC promoted myelin growth by activating PI3K/Akt/mTOR signal pathway in a rat chronic hypoperfusion model. Thirty adult ...

AIM The aim of this study was to evaluate the arterio-venous difference in carbon dioxide tension (DPCO2) and the ratio between DPCO2 and arterio-jugular oxygen difference (AJDO2) as indicators of compensated or uncompensated cerebral hypoperfusion. METHODS Cerebral blood flow (CBF) was reduced stepwise in 6 pigs by inducing intracranial hypertension with consequently cerebral perfusion press...

The influence of the duration of ischemia on the pattern of cerebral blood flow in recirculation was studied in anesthetised rats. Severe incomplete cerebral ischemia (mean ischemic flow = 5.8 +/- 0.4 ml/100 g/min) was produced by four-vessel occlusion and recirculation permitted after 15, 30 or 60 minutes ischemia. All three groups showed an immediate hyperemia followed by hypoperfusion. Hyper...

yncope is defined as loss of consciousness and postural tone due to transient global cerebral hypoperfusion. Although it may also manifest as transient loss of consciousness, epilepsy is not due to cerebral hypoperfusion, and its treatment differs markedly from that of syncope.1 A 66-year-old, right-handed man presented with a 11/2-year history of 2 to 3 episodes of syncope/month, usually prece...

Arthroscopic shoulder surgery is a common procedure and can be performed with the patient in the lateral decubitus position (LDP) or beach chair position (BCP). Although the BCP is associated with better visualization and less bleeding, it has also been associated with hemodynamic changes and consequently cerebral hypoperfusion. Devastating events reported after surgery in the BCP were attribut...