A significant percentage survival, representing a large number of viable cells, can occur in a Staphylococcus aureus population exposed to concentrations of mupirocin up to 1,000 times the minimum inhibitory concentration. An elevated ratio of minimum inhibitory to minimum bactericidal concentration of mupirocin with staphylococci was recorded. Staphylococci which survive exposure to mupirocin ...

In the present investigation, a series of 12 Mannich bases (QP1-12) and 5 Schiff bases (QSP1-5) of pyrazol-5(4H)-one moiety containing 3-(hydrazinyl)-2-phenylquinazolin-4(3H)-one has been synthesized and characterized by physicochemical as well as spectral means. The synthesized Mannich and Schiff bases were screened for their preliminary antimicrobial activity against Gram-positive and Gram-ne...

vibrio cholerae is a human pathogen that causes mild to severe diarrheal illnesses and has major public health significance. the aim of this study was to investigate the effects of antimicrobial activity of the gold nanoparticles on vibrio cholera. gold and silver nanoparticles are chemically synthesized. standard strain of vibrio cholerawas cultured in a nutrient broth. minimum inhibitory conc...

in our study, bioactivity of essential oil extracted from ginger (zingiber officinaleroscoe.) that belongs to family zingiberaceae was analyzed. ginger rhizome oil was found to be effective against a range of bio-deteriogens. the minimum inhibitory concentration (mic) value was determined by poisoned food technique and volatile activity assay. the study demonstrates that essential oil had a wid...

Garcinia atroviridis (Clusiaceae) has been used as a postpartum medication agent in folkloric medicine. However, its biological potential has not been fully evaluated. The present study was aimed to evaluate the antioxidant efficacies, cholinesterase enzyme inhibitory and antimicrobial activity of the stem bark extracts of G. atroviridis. Successive extraction was done using solvents of varied ...

High-dose daptomycin (DAP) therapy failed in a neutropenic patient with bloodstream infection caused by a DAP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 µg/mL) harboring genetic changes associated with DAP resistance, with persistent bacteremia and selection of additional resistances. Daptomycin monotherapy should be used cautiously against DAP-susceptible E. faecium ...

The significance Minimum Inhibitory Concentration (MIC) of determination for Meningococci is described and according to the present study a shift in the sensitivity of Meningococcus is occurring, local isolates show higher Minimum Inhibitory Concentration for Chloramphenicol and Azactam. Strains of Meningococcus can successfully be stored in a domestic freezer.

The minimum inhibitory concentrations of penicillin and cephalothin necessary to inhibit growth of most anaerobic bacteria were reduced to a susceptible level by 1 to 5 mug of clavulanic acid per ml. In most cases, minimum inhibitory concentrations of cefoxitin were not affected.