We read with interest the paper by Dr Alsaadi and colleagues on ‘‘potentially misleading extratemporal lobe lesions’’ in patients with symptoms of temporal lobe epilepsy. Most of their successfully operated patients with extratemporal lesions also had hippocampal atrophy on the operated side, which has positive prognostic value for mesiotemporal surgery in temporal lobe epilepsy, even in the pr...

[1] We point out the pitfall of using spatial patterns of correlation coefficients obtained from filtered data to infer physical mechanisms. Filtering is often used to emphasize a signal of interest by removing unrelated variability, but it alters subsequent correlation maps when the removed variance contains spatial structure, as is most often the case in geophysical applications. This then re...

The main signature of chaos in a quantum system is provided by spectral statistical analysis of the nearest-neighbor spacing distribution P(s) and the spectral rigidity given by the Delta(3)(L) statistic. It is shown that some standard unfolding procedures, such as local unfolding and Gaussian broadening, lead to a spurious saturation of Delta(3)(L) that spoils the relationship of this statisti...

Recanalization Rates Can Be Misleading To the Editor: We read with interest Rha and Saver’s1 review of relationships between recanalization and outcome and commend them on their comprehensive review of pertinent literature. However, we disagree with their main conclusion that recanalization may substitute for measurement of clinical outcome. The central finding that leads Rha and Saver1 to thei...

This article examines the relationships between interaction (product) terms and curvilinear (quadratic) terms in regression models in which the independent variables are correlated. The author uses 2 substantive examples to demonstrate the following outcomes: (a) If the appropriate quadratic terms are not added to the estimated model, then the observed interaction may indicate a synergistic (of...

David Oaks I would like to thank PLoS Medicine for publishing Lacasse and Leo’s important and methodical Essay that debunks the “chemical imbalance” advertisements for psychiatric drugs [1]. Why would the United States Food and Drug Administration (FDA) approve such ads? Our human rights group, MindFreedom International, has been asking that question for a long time. On behalf of MindFreedom, U...

We exhibit here, for a scalar theory, an apparently non-trivial Wilsonian fixed point, which surprisingly describes a free theory. This modest note is an observation which can be of interest in the framework of functional methods in Quantum Field Theory. The search for Wilsonian fixed points is important in Quantum Field Theory, as these represent configurations independent of the energy scale ...

Introduction Conclusions References

Osteoid osteoma is a benign bone tumor that when located on the base of the coracoids process of the scapula is very rare and diagnosis and treatment is often delayed because of its rarity. Almost any bone can be involved, but half of cases involve the femur or tibia. The radiologic features of osteoid osteoma are well known, but these tumors may present with unusual features and be easily misd...