نتایج جستجو برای: mm1 queue
تعداد نتایج: 13147 فیلتر نتایج به سال:
Reactive oxygen species (ROS) are metabolism by-products that may act as signaling molecules to sustain tumor growth. Antioxidants have been used to impair cancer cell survival. Our goal was to determine the mechanisms involved in the response to antioxidants of a human cell culture (PT4) containing glioblastoma (GBM) tumorigenic initiating cells (TICs). ROS production in the absence or presenc...
The massive star-forming core MM1 of W75N was observed using the Submillimeter Array with ∼1′′ and 2′′ spatial resolutions at 217 and 347 GHz, respectively. From the 217 GHz continuum we found that the MM1 core consists of two sources, separated by about 1′′: MM1a (∼0.6M ) and MM1b (∼1.4M ), located near the radio continuum sources VLA 2/VLA 3 and VLA 1, respectively. Within MM1b, two gas clump...
The oral proteasome inhibitor ixazomib is approved in the United States, European Union and other countries, in combination with oral lenalidomide and dexamethasone (Rd), for the treatment of patients with multiple myeloma who have received at least one prior therapy. Approval was based on the global, randomised, double-blind, placebo-controlled Phase III TOURMALINE-MM1 study of ixazomib-Rd (IR...
To appear in ApJS Water and Methanol Maser Survey of Protostars in the Orion Molecular Cloud Complex
The results of a maser survey toward ninety-nine protostars in the Orion molecular cloud complex are presented. The target sources are low-mass protostars identified from infrared observations. Single-dish observations were carried out in the water maser line at 22 GHz and the methanol class I maser lines at 44, 95, and 133 GHz. Most of the detected sources were mapped to determine the source p...
Recently tumor necrosis factor receptor super family member 18 (TNFRSF18, also called GITR) has been identified as a novel tumor suppressor gene in Multiple Myeloma (MM), undergoing aberrant DNA methylation-mediated gene expression silencing. Furthermore, the expression of GITR blocks canonical NF-κB activation in MM cells in response to TNFα. Bortezomib, a proteasome inhibitor, can induce NF-κ...
Background: Simulation is an appropriate technique for analyzing and evaluating the dynamic behavior of complex systems. The present study aimed to develop an integrated model using a simulation approach based on designing experiments to analyze performance of the admission queue system of patients, who referred to the emergency department of the Modarres hospital. Methods: In this descriptive...
In discrete event simulation, very often the future event set is represented by a priority queue. The data structure used to implement the queue and the way operations are performed on it are often crucial to the execution time of a simulation. In this paper a new priority queue implementation strategy, the Lazy Queue, is presented. It is tailored to handle operations on the pending event set e...
In this paper, we study the performance of service systems with priority upgrades. We model the service system as a single-server two-class priority queue, with queue 1 as the normal queue and queue 2 as the priority queue. The queueing model of interest has various applications in healthcare services, perishable inventory and project management. We comprehensively examine the system’s stationa...
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