نتایج جستجو برای: mmc model

تعداد نتایج: 2106802  

Journal: :Molecular cancer therapeutics 2012
Renjie Chen Dawei Zhang Yuan Mao Jin Zhu Hao Ming Juan Wen Jun Ma Qing Cao Hong Lin Qi Tang Jie Liang Zhenqing Feng

Nasopharyngeal carcinoma (NPC) is a major cause of cancer-related death in Southeast Asia and China. Metastasis and relapse are the primary cause of morbidity and mortality in NPC. Recent evidence suggests that the Epstein-Barr virus latent membrane protein 1 (LMP1) is exclusively expressed in most NPC and is a potential target for biotherapy. In this study, we successfully prepared a novel hum...

Journal: :The Journal of Experimental Medicine 1984
D Guy-Grand M Dy G Luffau P Vassalli

Gut mucosal mast cells (MMC), which are nearly absent in normal mice are abundant during nematode infection. In normal mice, study of MMC precursors (MMC-P: cells giving rise to MMC colonies in the presence of IL-3) show that: (a) their frequency, judged by limiting dilution is very high in bone marrow (BM) and gut, and very low in most lymphoid organs and thoracic duct lymph (TDL); (b) gut MMC...

2016
Ting Yang Yao Meng Li-Juan Chen Hong-Hui Lin De-Hui Xi

Alpha-momorcharin (α-MMC) is a type-I ribosome inactivating protein with a molecular weight of 29 kDa that is found in Momordica charantia, and has been shown to be effective against a broad range of human viruses as well as having anti-tumor activities. However, the role of endogenous α-MMC under viral infection and the mechanism of the anti-viral activities of α-MMC in plants are still unknow...

Journal: :Cancer research 1987
R Atsumi K Endo T Kakutani Y Takakura M Hashida H Sezaki

Disposition characteristics of the macromolecular prodrug of mitomycin C (MMC), mitomycin C-dextran conjugate (MMC-D), in normal and tumor (VX2 carcinoma)-bearing rabbit thigh muscles were studied using the in situ vascular perfusion technique. Three types of cationic MMC-D (MMC-Dcat) and two types of anionic MMC-D (MMC-Dan) with different carrier molecular weights were used. After bolus arteri...

Journal: :Journal of neurochemistry 2005
A Petzold D Stiefel A J Copp

Myelomeningocele (MMC), the most severe form of spina bifida (SB), causes neurological deficit. Injury to the spinal cord is thought to begin in utero. We investigated whether brain-specific proteins (BSPs) would enable us to monitor the development of MMC-related tissue damage during pregnancy in an animal model with naturally occurring SB (curly tail/loop tail mouse; n = 256). Amniotic fluid ...

Journal: :HPB Surgery 1992
Jin Wen Ding Zai de Wu Roland Andersson Stig Bengmark

Twelve mongrel dogs were randomly allocated into two groups using matched paired-design. Catheters were inserted into the hepatic artery, hepatic vein and the femoral vein, respectively. In the first group, gelfoam supplemented with mitomycin C (MMC) was injected into the hepatic artery, whereas the second group received a hepatic arterial injection of MMC solution alone. Simultaneous blood sam...

Journal: :IEEE Transactions on Power Electronics 2021

This letter assesses the impact of cyber-attacks on control system modular multilevel converter (MMC)-based high-voltage dc (MMC-HVdc) transmission technology. Specifically, small-signal model MMC-HVdc is characterized by a closed-loop matrix and distance to instability then quantified structured pseudospectrum. Furthermore, vertical search method proposed quantify boundary The quantification w...

Journal: :Cancer research 1996
K Mikami M Naito A Tomida M Yamada T Sirakusa T Tsuruo

Mitomycin C (MMC), a known cytotoxic agent, requires cellular enzyme-mediated activation for effective antitumor activity. To study the bioreductive enzymes responsible for MMC activation in tumor cells, we examined the enzyme activities of DT-diaphorase (DTD) and NADPH:cytochrome P-450 reductase in 13 colon and gastric carcinoma cell lines and then compared these activities to the respective c...

2014
Jody Ye Marta Vives-Pi Kathleen M. Gillespie

BACKGROUND Maternal microchimeric cells (MMc) transfer across the placenta during pregnancy. Increased levels of MMc have been observed in several autoimmune diseases including type 1 diabetes but their role is unknown. It has been suggested that MMc are 1) effector cells of the immune response, 2) targets of the autoimmune response or 3) play a role in tissue repair. The aim of this study was ...

Journal: :E3S web of conferences 2022

The MMC is composed of a large number sub-modules. operating conditions each sub-module are different, which will inevitably affect the capacitor voltage sub-module, resulting in difference sub-module. problem uneven system unavoidable, and greatly stable operation system. This paper studies multi-terminal flexible DC transmission (MMC-MTDC) based on modular multi-level converters. MMC-MTDC mod...

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