In this study, nonlinear bending of solid and annular functionally graded (FG) sector plates subjected to transverse mechanical loading and thermal gradient along the thickness direction is investigated. Material properties are varied continuously along the plate thickness according to power-law distribution of the volume fraction of the constituents. According to von-Karman relation for large ...

Nanoshell-mediated photothermal therapy (PTT) is currently being investigated as a standalone therapy for the treatment of cancer. The cellular effects of PTT include loss of membrane integrity, so we hypothesized that nanoshell-mediated PTT could potentiate the cytotoxicity of chemotherapy by improving drug accumulation in cancer cells. In this work, we validated our hypothesis using doxorubic...

Highly cross-linked polyethylene has become the gold standard in total hip replacement for its wear resistance. Moderately crosslinked polyethylene is now available for total knee replacement (TKR), although concerns about reduced mechanical strength have prevented widespread adoption. The purpose of this report is to describe an unusual case where a patient underwent cruciate retaining TKR usi...