Sir, Allergic contact dermatitis is the most common cause of peri-orbital eczema (1). It may be caused by allergens brought in contact with the eyelids by hand transfer (like toluene sulfonamide-formaldehyde resin in nail polishes), by airborne contact (like sesquiterpene lactones) or, most frequently, by direct application of cosmetics or topical ophthalmic medicaments. The percentage of sensi...

Colloidal oatmeal has been used for decades to soothe and ameliorate atopic dermatitis and other pruritic and/or xerotic dermatoses. In-vitro and/or in-vivo studies have confirmed the anti-inflammatory, barrier repair, and moisturizing properties of this compound. A broad set of studies has been conducted in recent years to assess the effects of colloidal oatmeal as adjunct treatment in the man...

Ever since Ervin Blank discovered1 the importance of moisturizing the stratum corneum, companies have focused their attention on developing a better surface barrier or improving skin surface moisturization in the outer layers of the stratum corneum. More recently, agents such as peroxisomal proliferator-activated receptor (PPAR) ligands have been developed and exploited in moisturizers. These a...

Background: Itch associated with cutaneous xerosis is a common condition, which can be effectively treated with the use of emollients combined with hydration therapy. The aim of our study was to evaluate the efficacy and tolerability of a new lotion containing menthol and colloidal oatmeal in patients with itch and cutaneous xerosis. Patients and Methods: Fifty-four patients with pruritus of di...

Frequent use of synthetic hair care products and overuse grooming results in damaged hair. This leads to growing demand for natural products. Many harsh chemicals liquid shampoo dry An attempt was made formulate a conditioning bar with safflower oil. The nutrient rich, weightless oil imparted good smoothness rough surface indicated by SEM studies treated containing 5% Formulated bars are found ...

Bleomycin hydrolase (BH) is expressed in the stratum granulosum and lower corneum (SC), which involved final filaggrin degradation. Furthermore, BH plays an essential role producing free amino acids, constitute majority of natural moisturizing factors (NMF). However, expression its protease activity associated with skin aging remain unclear. Thus, this study aimed to elucidate patterns SC extra...