The inclusion of main-chain tertiary amines in digital poly(phosphodiester)s allows synthesis molecularly-defined achiral polymers and simplifies tandem mass spectrometry sequencing.

Molecularly-uncharacterized organic matter comprises most reduced carbon in soils, sediments and natural waters. The origins, reactions and fates of these ubiquitous materials are relatively obscure, in large part because the rich vein of geochemical information that typically derives from detailed structural and stereochemical analysis is yet to be tapped. This discussion highlights current kn...

In this perspective, we discuss the cytoplasm in actively growing bacterial cells contrasted with viable but nonculturable (VBNC) cells. Actively growing bacterial cells contain a more molecularly crowded and organized cytoplasm, and are capable of completing their cell cycle resulting in cell division. In contrast, nutrient starving bacteria in the physiological VBNC state are struggling to su...

The development of in silico strategies for the study of the molecular imprinting process and the properties of molecularly imprinted materials has been driven by a growing awareness of the inherent complexity of these systems and even by an increased awareness of the potential of these materials for use in a range of application areas. Here we highlight the development of theoretical and compu...

molecularly targeted anticancer therapy with conventional cytotoxic chemotherapy. Such combinations can come about only through rational design of clinical trials, taking into account the pharmacology and clinical development of the drugs involved. It is therefore worthwhile revisiting classical chemotherapy agents, because this renewed knowledge could provide a foundation for future trials. Ox...

Synthesis of molecularly imprinted polymers vanillic acid and extraction from spiked blood serumShowkat Ahmad Bhawani, Salma Bakhtiar, Rachel Roland, Syed Rizwan Shafqat, Mohamad Nasir Ibrahim