To evaluate the efficacy of direct-acting antivirals (DAA) in patients with hepatitis C virus (HCV) associated cryoglobulinemia and monoclonal gammapathy (MG).

Multiple myeloma (MM) is one of the most important clonal malignant plasma cell disorders and renal involvement is associated with poor prognosis. Although there are several reasons for renal impairment in MM, the main cause is the toxic effects of monoclonal proteins. Although cast nephropathy is the best known and unchallenged diagnosis for hematologists and pathologists, the renal effects of...

a murine igm monoclonal antibody (ma-2c6) with κ-light chains directed against an antigenic determinant of outer surface protein a (ospa) of the lyme disease spirochete, borreliaburgdorferi, is produced. this antibody could bind specifically to ospa antigen of several isolates of b. burgdorferi, but not to the non-lyme disease bacteria such as t. pallidum and b. hermsii. antibody ma-2c6 was pur...

Twenty-four monoclonal antibodies were produced by immunizing BALB/c mice with Rickettsia tsutsugamushi Boryong strain and used for the analysis of antigenic characteristics of R.tsutsugamushi Boryong strain and antigenic heterogeneity of R.tsutsugamushi by indirect immunofluorescent(IF) test. R. tsutsugamushi Kato, Karp, Gilliam, TA686, TA716, TA763, TC586, TH1817, and Boryong were used for th...

Monoclonal antibodies targeting tumors are one of the most important discoveries in field cancer. Although several effective have been developed, a relapse may occur. One their mechanisms action is Antibody Dependent Cell Cytotoxicity (ADCC), by engaging Fc γ receptor CD16 expressing Natural Killer cells, innate lymphoid cells involved cancer immunosurveillance and able to kill tumor cells. A l...