germination is series of biochemical reactions that depends mainly on temperature and moisture. therefore, seed germination rate of lemon balm (mellissa officinalis l.) were evaluated in temperatures of 20, 23, 25,27, 30 and 32ºc and water potentials of 0, -0.2, -0.4, -0.6 and -0.8mpa. according to the results, germination temperature window was not very wide in a way that germination temperatu...

Paparan sinar UV matahari dapat merusak sel keratin bibir yang berfungsi melindungi bibir. Kosmetik biasa digunakan untuk melembabkan yaitu lip balm. Salah satu bahan alam mengandung antioksidan tinggi adalah Jeruk kalamansi dan bunga rosella. Penelitian ini bertujuan membuat sediaan Lip Balm dengan konsentrasi F1 4% sari buah jeruk kalamansi, F2 5% ekstrak rosella, F3 kombinasi ektrak Ekstraks...

BACKGROUND Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, which may result from alteration of the gastrointestinal microbiota following gastrointestinal infection, or with intestinal dysbiosis or small intestinal bacterial overgrowth. This may be treated with antibiotics, but there is concern that widespread antibiotic use might lead to antibiotic resistance. S...

The present study compares the gastrointestinal stability of rosmarinic acid in aqueous extracts of thyme, winter savory and lemon balm with the stability of pure rosmarinic acid. The stability of rosmarinic acid was detected after two-phase in vitro digestion process (gastric and duodenal) with human gastrointestinal enzymes. The concentration of rosmarinic acid in undigested and digested samp...

Remodeling of the local chromatin structure is essential for the regulation of gene expression. While a number of biochemical and bioimaging experiments suggest decondensed chromatin structures are associated with transcription, a direct visualization of DNA and transcriptionally active RNA polymerase II (RNA pol II) at super-resolution is still lacking. Here we investigate the structure of chr...

The purpose of this study was to investigate the anxiolytic effects of luteolin and its potential interaction with the gamma-aminobutyric acid (GABAA) receptor in male Sprague-Dawley rats. Lemon balm has traditionally been used as an herbal remedy in the treatment of many medical conditions, including anxiety. Luteolin is a major component of the essential oil lemon balm. We divided 55 rats int...

The concentrations of caffeic acid derivatives within Lamiaceae and Echinacea (herb, spice, tea, and dietary supplement forms) readily available in the US marketplace (n = 72) were determined. After the first identification of chicoric acid in Ocimum basilicum (basil), the extent to which chicoric acid could be found within the family Lamiaceae was investigated. The dominant phenolic acid in al...

Plant food additives are becoming more and popular broadly applied products, though the information on risks they poses to organism is limited contradictive. Obesity overeating some of commonest health issues around world, people increasingly consuming workability-enhancing preparations as a simple fast method weight control. The plant-based considered less harmful than synthetic chemical ones....

Methyl-CpG binding domain protein sequencing (MBD-seq) is widely used to survey DNA methylation patterns. However, the optimal experimental parameters for MBD-seq remain unclear and the data analysis remains challenging. In this study, we generated high depth MBD-seq data in MCF-7 cell and developed a bi-asymmetric-Laplace model (BALM) to perform data analysis. We found that optimal efficiency ...