Gastrointestinal (GI) discomforts are among the most common side effects of antiepileptic drugs (AEDs) that might lead to discontinuation or irregular consumption of the drugs. This study was conducted to evaluate the frequency of GI side effects of different AEDs in intractable epileptic patients treated with single or multiple drugs. GI discomfort of 100 epileptic patients (aged 35-76 years) ...

introduction: cyclic vomiting syndrome (cvs) is characterized by recurrent episodes of intense nausea and vomiting interpreted with symptom free period. as data regarding the pattern of disease in our region is scarce, we performed this study to investigate the pattern of pediatric cyclic vomiting in shiraz, southern iran. methods and patients: this study was performed in nemazee hospital, terr...

Autism spectrum disorder (ASD) is a genetically determined neurodevelopmental brain disorder presenting with restricted, repetitive patterns of behaviors, interests, and activities, or persistent deficits in social communication and social interaction. ASD is characterized by many different clinical endophenotypes and is potentially linked with certain comorbidities. According to current recomm...

During the transitioning through puberty, adolescents present with varied gynaecological issues, among which puberty menorrhagia is a significant complaint. The most common underlying cause of puberty menorrhagia is anovulation, other causes being endocrine dysfunction, PCOS and bleeding disorders. Congenital prothrombin deficiency is an extremely rare inherited coagulopathy, affecting one in t...

Vasculitis is an inflammatory disease of blood vessels that can affect all types of vessels in any organ of the body, including the vessels of the gastrointestinal (GI) tract. It may be secondary to systemic disorders, such as connective tissue disease (e.g., systemic lupus erythematosus, and rheumatoid arthritis), infection (e.g., bacterial endocarditis), malignancy, or drugs. Primary localize...

5 roton pump inhibitors (PPIs) suppress gastric acid secretion by selectively inhibiting the enzyme P hydrogenepotassium adenosine triphosphatase, located in gastric parietal cells. These drugs superseded H2-receptor antagonists as first-line acid suppressants in the 1980s, and their potent effect has revolutionised the management of common upper gastrointestinal (GI) disorders, including gastr...

Of 237 children with acute gastroenteritis in Antananarivo, Madagascar, during May 2004-May 2005, 14 ( 6%) were infected with norovirus. Seasonality (November-December peak) was detected. Reverse transcription-PCR identified GII as the most common genogroup. GIs belonged to GI.1, GI.3, and GI.4. Noroviruses in Madagascar show extensive genetic diversity.

Gastrointestinal (GI) fistula is a well-recognized complication of acute pancreatitis (AP). However, it has been reported in limited literature. This study aimed to evaluate the incidence and outcome of GI fistulas in AP patients complicated with infected pancreatic or peripancreatic necrosis (IPN).Between 2010 and 2013 AP patients with IPN who diagnosed with GI fistula in our center were analy...

BACKGROUND Henoch-Schönlein purpura (HSP) is a systemic vasculitic disorder commonly affecting young children. Gastrointestinal (GI) involvement is frequently seen, and it varies from mild symptoms to severe complications. METHODS In the 5 years from July 1995 to June 2000, 208 children were diagnosed with HSP in our hospital. There were 116 males and 92 females with ages ranging from 9 month...