The application of 2-photon laser scanning microscopy (TPLSM) techniques to measure the dynamics of cellular calcium signals in populations of neurons is an extremely powerful technique for characterizing neural activity within the central nervous system. The use of TPLSM on awake and behaving subjects promises new insights into how neural circuit elements cooperatively interact to form sensory...

Introduction: Robust motion correction is challenging in many MRI applications. Over the past two decades, several approaches have been proposed to suppress cardiac, respiratory or bulk motion [1-5]. We present a novel MOtion Correction method using Coil Arrays (MOCCA) that can be used for various motion corrections. In MOCCA, the elements of a coil array are used as individual motion “sensors”...

Introduction: Even a few millimeters of patient movement during an MRI exam can result in motion artifacts, manifested as blurring or ghosting, that render the images diagnostically unusable. Often, in subject populations with a high potential diagnostic benefit, e.g. young children, elderly subjects, and patients with dementia, the utility of MRI is curtailed by motion artifacts, underlining t...

This article presents a motion compensation procedure that significantly improves the accuracy of synthetic aperture tensor velocity estimates for row-column arrays. The proposed scheme reduces effects by moving image coordinates with field during summation low-resolution volumes. is estimated using transverse oscillation cross-correlation estimator, and each coordinate's local determined upsam...

BACKGROUND Image registration algorithms are frequently used to align the reconstructed brain PET frames to remove subject head motion. However, in occupancy studies, this is a challenging task where competitive binding of a drug can further reduce the available signal for registration. The purpose of this study is to evaluate two kinds of algorithms-a conventional frame-by-frame (FBF) registra...