Fischer et al. [1] report that theophylline improves acute mountain sickness (AMS). This is of high interest, as there may be an adenosine-sensitive mechanism of hypoxic respiratory control and therapy, with a specific adenosine antagonist like theophylline, which may potentially influence respiratory adaptation to hypoxia. However, recent studies in human and animal experiments, which sought t...

INTRODUCTION Headache is the most common complication associated with exposure to high altitude, and can appear as an isolated high-altitude headache (HAH) or in conjunction with acute mountain sickness (AMS). The purpose of this article is to review several aspects related to diagnosis and treatment of HAH. DEVELOPMENT HAH occurs in 80% of all individuals at altitudes higher than 3000 meters...

The acute ventilatory response to hypoxia (HVR) and to hypercapnia (CO2VR) was measured in 32 members of two mountaineering expeditions prior to their departure. Both teams made rapid ascents to their base camps at 5200 m and 4300 m and remained there for at least four days. Symptom scores for acute mountain sickness (AMS) were collected daily for these four days. There was a range of AMS from ...

The Everest Marathon in the Nepal Himalayas has been run every 18 months since 1987, from Gorak Shep near Everest Base Camp to Namche Bazaar. This is a 26.2 mile marathon run from a starting altitude of 5184 m above sea level down to 3664 m over exceptionally difficult terrain. The route is predominantly downhill, although there are two steep uphill sections, with the ground underfoot varying f...

Acute mountain sickness (AMS) is the most common form of illness at high altitude; however, it still unclear whether age a protective factor or risk for development AMS in travellers. The condition generally occurs altitudes higher than 8,000 feet (ft), 2,500 meters (m), and usually due to lack oxygen. A person who not used developing altitude sickness. Mountain also called sickness, referring ...

Acute mountain sickness (AMS) occurs commonly in hikers who are rapidly exposed to high altitude environments. Despite the numerous reports of AMS, few studies have reported pallidal lesions associated with altitude sickness. A previously healthy 49-yr-old Korean patient, after ascent to 4,700 m, suffered symptoms consistent with AMS. After returning home, the patient showed changes in personal...