We report the applicability of testing susceptibility to paranitrobenzoic acid (PNB) directly on clinical samples as a rapid screening assay, to detect M. tuberculosis and differentiate it from non-tuberculous mycobacteria (NTM). One hundred smear positive sputum samples from patients with pulmonary tuberculosis attending the Department of Respiratory Medicine at VP Chest Institute, Delhi, were...

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The recently developed ESP Culture System II (AccuMed, Chicago, Ill.) was compared with radiometric BACTEC 460TB (Becton Dickinson, Towson, Md.) and with Lowenstein-Jensen medium for recovery of mycobacteria from over 2,500 clinical specimens both of respiratory and nonrespiratory origin, including blood. The majority of the 219 mycobacterial isolates (129) belonged to the Mycobacterium tubercu...

background : multi drug-resistant mycobacterium tuberculosis (mdr-tb) is an infection with a causative bacillus which is resistant to at least two drugs, isoniazid and rifampin. the purpose of this study is to evaluate the prevalence of tb resistance to first-line drugs of newly diagnosed active pulmonary tuberculosis. methods : this cross-sectional study was performed on 77 patients with newly...

BACKGROUND There is an urgent need for low-cost methods for rapid, accurate detection of Mycobacterium tuberculosis in clinical specimens. The microscopic-observation drug-susceptibility (MODS) assay is a relatively low-cost and simple liquid culture method that has been proposed for use in resource-limited environments. METHODS This prospective study evaluated the performance of the MODS ass...

[PDF] [Full Text] [Abstract] , October 15, 2008; 28 (20): 6248-6261. Mol. Cell. Biol. O. C. Velazquez and S. R. Thom T. N. Milovanova, V. M. Bhopale, E. M. Sorokina, J. S. Moore, T. K. Hunt, M. Hauer-Jensen, Autocrine Activation Loop Involving Hypoxia-Inducible Factor 1 Lactate Stimulates Vasculogenic Stem Cells via the Thioredoxin System and Engages an [PDF] [Full Text] [Abstract] , Februa...

Multi-dimensional @I-D) fast Fourier transform (FFT) is an essential algorithm in array signal processing. However, the calculation of M-D indexing and transposition of data matrix required by the M-D FFT are the algorithm's performance killer. The paper will propose a novel M-D to l-D FFT signal flow graph (SFG) mapping. Thus, the M-D FlV can be efficiently implemented by the unified l-D index...