Behavioral and electrophysiological evidences have shown that locus ceruleus (LC) is involved in different tasks including modulation of sensory processing and shift of attention. In the present study, single unit responses of barrel cortical cells was recorded following controlled mechanical displacement of the principal and peripheral vibrissae in adult rats (100 trials of 200 µm deflection f...

Purpose Atmospherics is undoubtedly a multi-sensory concept, despite mostly being studied on sense-by-sense basis by architects, sensory marketers and urban designers alike. That is, our experience nearly always the result of cross-modal/multi-sensory interactions between what we see, hear, smell feel in given space. As such, it critical that researchers study senses concert. said, few empirica...

Abstract Objective. The rapid acceleration of tools for recording neuronal populations and targeted optogenetic manipulation has enabled real-time, feedback control circuits in the brain. Continuously-graded measured activity poses a wide range technical challenges, which we address through combination stimulation state-space optimal framework implemented thalamocortical circuit awake mouse. Ap...

The hypothesis that discharges from afferent nerves from muscle stretch receptors do not participate in kinesthesis has been substantiated by test of discrimination thresholds. In awake, unrestrained cats, nerve stimulation activating group I and most group II sensory fibers (from muscle spindles and Golgi tendon organs) in pure muscular nerves failed to evoke sensory discrimination. Cutaneous ...

BACKGROUND AND OBJECTIVES Continuous sciatic nerve blockade at the popliteal level effectively alleviates postoperative pain after major foot and ankle surgery. No randomized controlled trials have previously compared the success rate of continuous sciatic nerve sensory blockade between ultrasound and nerve stimulation guidance. In the current study, we tested the hypothesis that ultrasound-gui...

The tail-withdrawal reflex of Aplysia can be sensitized by weak stimulation of a site outside the site used to test the reflex or by repeatedly stimulating the test site itself. The sensitization of tail-withdrawal responses is associated with enhanced activation of the tail motor neurons and heterosynaptic facilitation of the monosynaptic connections between the tail sensory neurons and tail m...

The main effects and interaction of pulse duration and pulse charge on sensory, motor and painful stimulation were examined on six male subjects. Surface electrodes were placed over the triceps brachii muscle. Pulse duration was varied between 5 and 1000 µs. Peak current, muscle torque and four excitatory responses were determined. Sequential order of sensory, motor and painful stimulation was ...