نتایج جستجو برای: multicomponent reactions mcrs

تعداد نتایج: 175438  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
Andrew J Aguirre Cameron Brennan Gerald Bailey Raktim Sinha Bin Feng Christopher Leo Yunyu Zhang Jean Zhang Joseph D Gans Nabeel Bardeesy Craig Cauwels Carlos Cordon-Cardo Mark S Redston Ronald A DePinho Lynda Chin

The pancreatic adenocarcinoma genome harbors multiple amplifications and deletions, pointing to the existence of numerous oncogenes and tumor suppressor genes driving the genesis and progression of this lethal cancer. Here, array comparative genomic hybridization on a cDNA microarray platform and informatics tools have been used to define the copy number alterations in a panel of 24 pancreatic ...

2014
Kelly N. Chuh Balyn W. Zaro Friedrich Piller Véronique Piller Matthew R. Pratt

Metabolic chemical reporters (MCRs) of glycosylation are analogues of monosaccharides that contain bioorthogonal functionalities and enable the direct visualization and identification of glycoproteins from living cells. Each MCR was initially thought to report on specific types of glycosylation. We and others have demonstrated that several MCRs are metabolically transformed and enter multiple g...

1998
Ufuk Yıldız Baki Hazer

In order to evaluate the gelation behavior of macromonomeric azoinitiators (MIMs), the free radical polymerization of MIM and macrocrosslinkers (MCRs) have been compared. MIMs were synthesized by the reaction between 4,49-dicyano-4,49-azovaleryl chloride and poly(ethylene glycol)s PEG-400, -1000, -1500, -2000 and 4-vinylbenzyl chloride. MCRs were obtained by vinylation of both hydroxyl ends of ...

Journal: :Journal of the American Chemical Society 2015
Nicklas Deibl Kevin Ament Rhett Kempe

Since alcohols are accessible from indigestible biomass (lignocellulose), the development of novel preferentially catalytic reactions in which alcohols are converted into important classes of fine chemicals is a central topic of sustainable synthesis. Multicomponent reactions are especially attractive in organic chemistry as they allow the synthesis of large libraries of diversely functionalize...

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