In a recent publication 1 the author recorded the results of a chemical analysis of blood sera from different diseased conditions. It was observed that the proteins of the serum are subject to extensive variations, and in certain diseases the globulin fraction in the serum is greatly increased. In the serum of cases of chronic parenchymatous nephritis the increase in the globulin content is mos...

INTRODUCTION Renal injury due to sarcoidosis develops in less than a quarter of patients with this systemic disease. In most cases, granulomatous tissue alters the production of vitamin D, which leads to hypercalciuria, nephrocalcinosis, and nephrolithiasis. Granulomatous interstitial nephritis is another well-recognized pathological process associated with sarcoidosis. However, a glomerular pa...

This article explores a non-invasive method to determine interstitial fluid level and pressure in tissue. Interdigital electrodes were chosen by simulated results in software "Comsol multiphysis 4.3a". Environment model similar to human body was created. Measurements were carried out at different situations which can occur during preoperative and afterwards surgery. Non-invasive method decrease...

We report a case of acute interstitial nephritis (AIN), most likely induced by rosuvastatin, in an 83-year-old male patient. The patient underwent angioplasty of the left internal carotid artery, after which he began a regimen of rosuvastatin (20 mg/day). After 3 weeks the patient was admitted to our unit for acute renal failure with mild proteinuria with negligible urinary sediment. A left kid...

Interstitial nephritis was diagnosed at renal biopsy in 10 previously healthy children. All had identical clinical symptoms: anaemia, raised sedimentation rate, low glomerular filtration rate, protein and leucocytes in the urine, but no bacteria; nine also had glycosuria. Six of the children had a history of recent ingestion of drugs or a serologically proved infection, or both. One child later...

Introduction Diflunisal has been reported as causing acute allergic interstitial nephritis (Chan et al., 1980) resulting in acute oliguric renal failure. A case of acute renal failure due to tubulo-interstitial nephritis after 3 months of diflunisal is reported here. Recently, phenylakalonic acids with analgesic and antiinflammatory properties such as fenoprofen and naproxen have been reported ...

Fluoroquinolones are generally well tolerated, clinically useful antimicrobials. This paper highlights rare, but potentially serious, adverse effects involving the kidney. Other antimicrobials have long been known to cause various forms of nephrotoxicity occurring as allergic interstitial nephritis, granulomatous interstitial nephritis, necrotising vasculitis, allergic tubular nephritis or a tu...

Background: Sarcoidosis is a multi-system disorder characterized by noncaseating epitheloid granuloma in multiple organs. However, granulomatous interstitial nephritis in the absence of extrarenal renal lesions is very rare. Case presentation: A 64-year-old male presented with a weight loss of 10 kg and an increase in serum creatinine from 1.1 to 4.8 mg/dl over a 1-year period. At admission, no...

acute yew (taxus baccata) intoxication was induced in 7 adult sheep by oral administration of the plant materials at the dose of 2.5g/kg body weight. blood samples for hematology and serum biochemistry were collected before and after the induced intoxication.electrocardiography was performed using a base-apex lead. intoxicated animals displayed lethargy, depression, bradycardia and varying inte...

Acute interstitial nephritis (AIN) is characterized by inflammation of the renal interstitium and usually occurs in a temporal relationship with the medication. We present a case of an Asian male who had nephrotic range proteinuria and presented with acute kidney injury. The patient reported an acute change in physical appearance and symptomatology after the ingestion of a single dose of silden...