BACKGROUND AND PURPOSE Asymptomatic carotid artery stenosis can lead to not only stroke but also cognition impairment. Although it has been proven that carotid artery stenting (CAS) can reduce the risk of future strokes, the effect of CAS on cognition is conflicting. In recent years, pulsed arterial spin labeling (pASL) MRI and resting-state functional MRI (R-fMRI) have been employed in cogniti...

BACKGROUND Cognitive decline in multiple sclerosis (MS) negatively impacts patients' everyday functioning and quality of life. Since symptomatic pharmacological treatment is not yet available alternative treatment strategies such as cognitive rehabilitation are of particular interest. OBJECTIVES To analyse the ways in which MS patients respond to cognitive training, by combining behavioral an...

multiple sclerosis (ms) is an autoimmune disease of the central nervous system (cns) which causes demyelination of the nerve fibers. the etiology of this disease is not well understood but it is believed that t helpers play a central role in ms. numerous findings support the view that th17 cells play an essential role in pathogenesis of ms and il-17 secreting t (th17) cells have a role in infla...

when pooled immunoglobulin g (igg) from patients with multiple sclerosis (ms) was used to probe a human fetal spinal cord λgt 11 cdna library, the igg was found to bind to a predicted epitope of human mitochondrial nd4 sequence. to investigate the involvement of the nd4 as an autoantigen in ms, we determined the presence of specific antibody in the serum of ms patients and serum samples of some...

conclusions components of social support, totally account for 19% of resiliency variance value of patient; the components of social support, family, friends, and other people’s support at only had lower contribution in predicting resiliency. support of this group of people to increase their resiliency seems necessary. results there was a significant association between social support and resili...

background: multiple sclerosis (ms) is a chronic disease characterized by degradation of the central nervous system myelin which may impair the balance of patients. core stability exercises have been the focus of attention for repairing the stability of some patients.   objectives: to assess the effect of core stability exercise on the balance of patients with multiple sclerosis. materials and ...

Major depressive disorder (MDD) is highly prevalent, recurrent, and associated with functional impairment, morbidity, and mortality. Herein, we aimed to identify disruptions in functional connectomics among subjects with MDD by using resting-state functional magnetic resonance imaging (rs-fMRI). Sixteen subjects with MDD and thirty health controls completed resting-state fMRI scans and clinical...

It remains an ongoing investigation about how the neural activity alters with the diurnal rhythms in human brain. Resting-state functional magnetic resonance imaging (RS-fMRI) reflects spontaneous activities and/or the endogenous neurophysiological process of the human brain. In the present study, we applied the ReHo (regional homogeneity) and ALFF (amplitude of low frequency fluctuation) based...