OBJECTIVE Muscle injuries are common, and their treatment requires costs and time off. Platelet rich plasma and low level laser therapy have been shown to be affordable and easy to use. The aim of this study was to evaluate the associated effects of low level laser therapy and platelet rich plasma on the treatment of the soleus muscle injured by strain in rats. METHODS Thirty-five rats were r...

C rush injury leading to rhabdomyolysis is one of the dreaded complications of natural catastrophes such as earthquakes. Rhabdomyolysis is a syndrome characterized by muscle necrosis and the release of intracellular muscle constituents, namely creatine phosphokinase, myoglobin, and various electrolytes into the circulation. Precipitation of myoglobin in the renal tubules with secondary obstruct...

hemorrhoidectomy is the treatment of choice for patients with third or fourth-degree hemorrhoids. although the majority of surgeons believe that surgical hemorrhoidectomy is the most effective approach with excellent results in the management of hemorrhoid disease, but hemorrhoidectomy is not a simple procedure. one of the complications of this surgery is an injury to anal sphincters that can l...

Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth muscle cells, the effects of mebendazole on vascular smooth muscle cell proliferation were tested in vitro and in a mouse model of arterial injury. ...

TGF-β1 is known to inhibit muscle regeneration after muscle injury. However, it is unknown if high systemic levels of TGF-β can affect the muscle regeneration process. In the present study, we demonstrated the effect of a CCl4 intra-peritoneal injection and losartan (an angiotensin II type 1 receptor antagonist) on skeletal muscle (gastrocnemius muscle) injury and regeneration. Male C57BL/6 mic...

Rhabdomyolysis constitutes an uncommon cause of acute kidney injury (AKI). A large variety causes with different pathogenic mechanisms may involve skeletal muscles resulting in rhabdomyolysis or without injury. Crush syndrome and unaccustomed physical exertion are the most common rhabdomyolysis. This study reports local cases AKI secondary to that presented a tertiary care centre over period fo...

Frontal vehicle collisions can cause injury to a driver's cervical muscles resulting from intense changes in muscle strain and muscle load. This study investigated the influence of collision forces in a sled test environment using a modified Hybrid III 50th percentile dummy equipped with simulated spring-type muscles. Cervical muscle responses including strain and load of the sternocleidomastoi...

BACKGROUND Many patients taking statins often complain of muscle pain and weakness. The extent to which muscle pain reflects muscle injury is unknown. METHODS We obtained biopsy samples from the vastus lateralis muscle of 83 patients. Of the 44 patients with clinically diagnosed statin-associated myopathy, 29 were currently taking a statin, and 15 had discontinued statin therapy before the bi...

background & aim: pain is a major problem after burn injury. therapeutic practices do not provide suffi-cient pain relief for patients with burn. therefore, non-pharmacological interventions such as muscle relaxa-tion and mental imagery can be effective in reducing pain. this study aimed to compare the effects of mus-cle relaxation and mental imagery techniques on pain intensity in patients wit...

Muscle damage and myopathy-like changes can occur following strenuous and unccustomed exercise, particularly activity involving eccentric contractions. The associated strength loss can have a long lasting impact on performance. The question of how eccentric contraction induced injury effects muscle performance and what mechanism(s) account for the strength loss is addressed in this review by fo...