نتایج جستجو برای: muscle pathology

تعداد نتایج: 431307  

Journal: :The European respiratory journal 2008
A H Remels H R Gosker P Schrauwen R C Langen A M Schols

Extrapulmonary pathology significantly impairs clinical outcome in chronic obstructive pulmonary disease (COPD). The peroxisome proliferator-activated receptors (PPARs) are implicated in the regulation of several hallmarks of systemic COPD pathology, including cachexia, decreased oxidative muscle metabolism, oxidative stress and systemic inflammation. Recently, expression of PPARs and related c...

Journal: :The Journal of bone and joint surgery. British volume 2003
J Zammit D Singh

Whilst a few studies have associated various symptoms with the presence of a peroneus quartus muscle in the peroneal compartment of the leg, little is known of the clinical relevance of this muscle. We dissected 102 cadaver legs and reviewed the magnetic resonance images of 80 patients with symptoms from the ankle. The peroneus quartus, with a number of different attachments, was present in 6.6...

Journal: :Human molecular genetics 2013
Michael W Lawlor Dustin Armstrong Marissa G Viola Jeffrey J Widrick Hui Meng Robert W Grange Martin K Childers Cynthia P Hsu Michael O'Callaghan Christopher R Pierson Anna Buj-Bello Alan H Beggs

No effective treatment exists for patients with X-linked myotubular myopathy (XLMTM), a fatal congenital muscle disease caused by deficiency of the lipid phosphatase, myotubularin. The Mtm1δ4 and Mtm1 p.R69C mice model severely and moderately symptomatic XLMTM, respectively, due to differences in the degree of myotubularin deficiency. Contractile function of intact extensor digitorum longus (ED...

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