Resveratrol (3,5,4-trihydroxy-trans-stilbene), which is found in grapes and red wine has been shown to protect neuronal cells with its antioxidant activity, improve memory function in dementia and reverse acetylcholine esterase (AChE) activity. The aim of this study was to investigate the effect of resveratrol on emotional and spatial memory in naive rats, as well as on scopolamine- and mecamyl...

Since close relationship was shown between drug addiction and memory formation, the aim of the present study was to investigate the effects of interaction between prenatal methamphetamine (MA) exposure and MA treatment in adulthood on spatial and non-spatial memory and on the structure of the N-methyl-D-aspartate (NMDA) receptors in the hippocampus. Adult male rats prenatally exposed to MA (5 m...

We study the problem of finding a maximummatching in a graph given by an input stream listing its edges in some arbitrary order, where the quantity to be maximized is given by a monotone submodular function on subsets of edges. This problem, which we call maximum submodular-function matching (MSM), is a natural generalization of maximum weight matching (MWM), which is in turn a generalization o...

The Morris water maze is one of the most extensively used tools in behavioral neuroscience to investigate spatial learning and memory [1]. MWM learning is thought to rely extensively on hippocampus, and involves several major neurotranmitter systems. One such major neurotransmitter system of great importance is the cholinergic system [2]. Scopolamine, a muscarinic cholinergic antagonist, is kno...

The current study sought to determine whether prenatal 3,4-methylenedioxy-N-methamphetamine (MDMA) exposure from E14-20 in the rat resulted in behavioral sequelae in adult offspring. Prenatal MDMA exposure results in increased dopaminergic fiber density in the prefrontal cortex, striatum and nucleus accumbens of young rats. Since these areas are critical in response to novelty, reward, attentio...

The aim of the present study was to investigate the impact of prenatal methamphetamine (MA) exposure and application of the same drug in adulthood on cognitive functions of adult male rats tested in Morris water maze (MWM). Adult male rats prenatally exposed to MA (5 mg/kg), saline or no injection were examined. Half of the animals were injected daily with MA (1 mg/kg) after finishing the testi...

Honey has shown potential therapeutic properties in traditional medicine. This study investigated the cognition enhancing potential of Tualang honey in chronic cerebral hypoperfusioninduced neurodegeneration by permanent bilateral common carotid arteries ligation (2 vessels occlusion2VO) in rats. Previous studies have shown that rats subjected to 2VO (2 vessel occlusion) experienced cognitive d...

The input queued (IQ) crossbar based switching, employing virtual output queueing (VOQ), is the dominant architecture for high-performance packet switches. The performance of a VOQ switch depends solely on the scheduling algorithm used. Maximum Weight Matching (MWM) algorithms have optimal performance however they are not practical due to their hardware complexity. Round Robin (RR) based algori...

Maternal separation (MS) has been demonstrated to up-regulate the hypothalamic vasopressin (VP) system. Intracerebrally released VP has been demonstrated to affect several types of animal behaviour, such as active/passive avoidance, social recognition, and learning and memory. However, the role of VP in spatial learning remains unclear. In the present study, we investigated the effects of an os...

Studies showed that stimulant drugs that affect the monoaminergic system alter both behavioral and cognitive processes. The aim of the present study was to investigate the impact of prenatal and acute methamphetamine (MA) exposure on cognitive functions of adult male rats tested in Morris water maze (MWM). We tested adult male rats prenatally exposed to MA (5 mg/kg), saline or no injection. Hal...