نتایج جستجو برای: myoepithelial carcinoma

تعداد نتایج: 395099  

Journal: :The Journal of pathology 2017
Hendrika M Duivenvoorden Jai Rautela Laura E Edgington-Mitchell Alex Spurling David W Greening Cameron J Nowell Timothy J Molloy Elizabeth Robbins Natasha K Brockwell Cheok Soon Lee Maoshan Chen Anne Holliday Cristina I Selinger Min Hu Kara L Britt David A Stroud Matthew Bogyo Andreas Möller Kornelia Polyak Bonnie F Sloane Sandra A O'Toole Belinda S Parker

Mammography screening has increased the detection of early pre-invasive breast cancers, termed ductal carcinoma in situ (DCIS), increasing the urgency of identifying molecular regulators of invasion as prognostic markers to predict local relapse. Using the MMTV-PyMT breast cancer model and pharmacological protease inhibitors, we reveal that cysteine cathepsins have important roles in early-stag...

2015
Bruno Tavares Sedassari Maria Fernanda Setúbal Destro Rodrigues Fernanda Viviane Mariano Albina Altemani Fábio Daumas Nunes Suzana Sousa Bruno Tavares Sedassari.

In the present study, we evaluated and described the sensitivity of the stem cell marker B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) in identifying early lesions of carcinoma ex pleomorphic adenoma (CXPA). While invasive CXPAs are tumors with a prominent and easily recognizable malignant component, the identification of early carcinomatous changes in PA remains a di...

Journal: :American journal of clinical pathology 2005
Jorge Albores-Saavedra Steven Cooper Heard Bernadette McLaren Hideko Kamino Agnieszka K Witkiewicz

We compared 4 breast cylindromas with 50 dermal cylindromas and 8 adenoid cystic breast carcinomas. Except for a modest increase in the number of eccrine ducts and reactive Langerhans cells in dermal cylindromas, breast and dermal cylindromas showed identical histologic and immunohistochemical features. Both were characterized by epithelial islands containing central basaloid cells and peripher...

Journal: :Journal of case reports 2021

Background: Sclerosing polycystic adenosis (SPA) is a rare, recently described, tumorous condition of the major or minor salivary glands that on gross and microscopic evaluation mimics an invasive carcinoma. The histology quite similar to seen in fibrocystic disease, sclerosing tumors breast. It also resembles more diffuse bilaterally occurring dysgenetic disease (PDD) parotid gland. To best ou...

Journal: :Saudi Journal of Medical and Pharmaceutical Sciences 2020

Journal: :Brazilian journal of otorhinolaryngology 2016
Fernanda Viviane Mariano Karina Giovanetti Luis Fernando Vidal Saccomani André Del Negro Luiz Paulo Kowalski Ana Cristina Victorino Krepischi Albina Altemani

INTRODUCTION A key step of cancer development is the progressive accumulation of genomic changes resulting in disruption of several biological mechanisms. Carcinoma ex-pleomorphic adenoma (CXPA) is an aggressive neoplasm that arises from a pleomorphic adenoma. CXPA derived from a recurrent PA (RPA) has been rarely reported, and the genomic changes associated with these tumors have not yet been ...

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