trans-3-Hydroxy-nn-proline-3,4-3H was synthesized by reduction of N-carbobenzoxy-3-keto-DLproline methyl ester with NaBH4 (4). Uniformly labeled n-proline-r4C was obtained from New England Nuclear Corporation. Uniformly labeled 4-hydroxy-r.-prolineJ4C was generously donated to us by Dr. Chozo Mitoma. Seven-day-old chick embryos were obtained from the Duckworth Hatchery (Elkridge, Maryland) and ...

An analytical method for dimethyl sulfoxide (DMSO) in aqueous samples at nanomolar levels has been improved. DMSO was reduced to dimethyl sulfide (DMS), concentrated on an adsorbent, and measured by gas chromatography. In the presence of iron chloride, the sodium borohydride (NaBH4) reduction of DMSO proceeded smoothly and efficiently, and the repeatability of this reaction was significantly im...

trans-3-Hydroxy-nn-proline-3,4-3H was synthesized by reduction of N-carbobenzoxy-3-keto-DLproline methyl ester with NaBH4 (4). Uniformly labeled n-proline-r4C was obtained from New England Nuclear Corporation. Uniformly labeled 4-hydroxy-r.-prolineJ4C was generously donated to us by Dr. Chozo Mitoma. Seven-day-old chick embryos were obtained from the Duckworth Hatchery (Elkridge, Maryland) and ...

Sodium-based complex hydrides have recently gained interest as electrolytes for all-solid-state batteries due to their light weight and high electrochemical stability. Although room temperature conductivities are not sufficiently battery application, nanocomposite formation with metal oxides has emerged a promising approach enhance the ionic conductivity of hydrides. This enhancement is general...

NaBH4 (1.25 equivalents) & NaNO3 (3 equivalents) reduce a variety of aldehydes in the presence of ketones to their corresponding alcohols. Also, regioselectivity and exclusive 1,2reduction enals to their corresponding allylic alcohols in high to excellent yields was achieved successfully with this reducing system. The reduction reactions were carried out in water as green solvent in high to exc...

S-Adenosylmethionine decarboxylase from Saccharomyces cerevisiae has been purified to homogeneity. Acid hydrolysis of NaB3H4-reduced enzyme released 2.2 mol of tritiated lactate per mol of dimeric enzyme, indicating that a pyruvate moiety is present. Inhibition of enzymatic activity by NaBH4 reduction and by carbonyl-binding reagents indicates that this pyruvoyl residue is required for the acti...

An operationally simple and environmentally benign formal hydrogenation protocol has been developed using highly abundant iron(iii) salts and an inexpensive, bench stable, stoichiometric reductant, NaBH4, in ethanol, under ambient conditions. This reaction has been applied to the reduction of terminal alkenes (22 examples, up to 95% yield) and nitro-groups (26 examples, up to 95% yield). Deuter...

Reduction of human 5-aminolaevulinate dehydratase with NaBH4 in the presence of 14C-labelled substrate led to complete loss of catalytic activity and to incorporation of label into the enzyme protein. By comparison with authentic lysyl-aminolaevulinic acid, prepared chemically, the modified active-site amino acid obtained by acid hydrolysis was shown to be lysine. Sequencing of a CNBr-cleavage ...

An array of Pd–W alloys was fabricated, and the electrocatalytic activity of the alloys for the oxygen reduction reaction (ORR) in acidic media was screened by scanning electrochemical microscopy. The Pd0.7W0.3 showed the highest activity for the ORR, close to that for Pd0.8Co0.2 and Pt. A Pd–W electrocatalyst loaded on carbon black was formed by the NaBH4-reduction method, exhibiting high acti...

In the presence of water lithium tetrahydroborate is capable of reducing pyridine to 1,4dihydropyridine. The product, lithiumtetrakis(pyridine) tetrakis(1,4-hydropyridyl)borate, was isolated and characterized by NMR and IR spectroscopy and single crystal X-ray diffraction. [Li(py)4][B(pyH)4]2(1,4-dioxane) crystallized in space group P42/n, Z = 2. Similarly, NaBH4 can also reduce pyridine in the...