Ectodermal dysplasias are conditions that present primary defects in two or more tissues of ectodermal origin and can be classified as hypohidrotic and hidrotic. Hidrotic ectodermal dysplasia or Clouston syndrome is an autosomal dominant genodermatosis and appears as a triad of clinical findings: palmoplantar keratoderma, nail dystrophy, and hypotrichosis. The hair is sparse and brittle. The na...

ZinsserCole-Engman syndrome, also known as dyskeratosis congenita, is a rare genetic disorder characterized by triad of pigmentation and atrophy of the skin, leukokeratoses of oral mucosa and nail dystrophy along with bone marrow failure and predisposition to cancer [1]. The condition can be inherited as autosomal recessive, autosomal dominant and rarely X linked. It is proposed that mutations ...

background: nail disorders comprise approximately 10% of all dermatological conditions. abnormalities in the color of nails are called ungal dyschromia or chromonychia. ungual dyschromia may be endogenous or exogenous. yellow discoloration of the nails has been reported during the last years as separate observation related to drug administration, during hemodialysis and associated with pulmonar...