The main toxin of Naja naja samarensis is a very small and rigid protein (Mr 6850, 8 cysteines). When fully reduced, it regains its native conformation by a mechanism involving a rapid cysteine oxidation and a slower, less temperature-dependent disulfide exchange. In a native-like form of the protein we observed a population whose cysteines were incompletely reoxidized. When intermediates with ...

The complex chemical nature of Indian cobra (Naja naja) venom was indicated by Ganguly & Malkana (1936) and Ganguly (1937), who reported its percentage composition as follows: total protein 87-56, globulin 20*31, albumin 39-69, primary proteose 11 31, secondary proteose 16-81. In addition to proteins, the venom was found to contain cholesterol, phospholipins, inorganic substances and colouring ...