نتایج جستجو برای: namd
تعداد نتایج: 319 فیلتر نتایج به سال:
PURPOSE To report (1) the costs of verteporfin photodynamic therapy (VPDT) in routine treatment of neovascular age-related macular degeneration (nAMD), (2) the relationship between health and social service costs and best-corrected visual acuity (BCVA), (3) the cost-effectiveness of VPDT versus a best supportive care (BSC) group who were assumed to have no active treatment, and (4) lessons for ...
INTRODUCTION The aim of this study was to determine treatment delivery patterns for patients with neovascular age-related macular degeneration (nAMD) across the UK through an ophthalmology trainee research network delivered observational study. METHODS Data were collected via an online tool by potential research collaborators identified by the Ophthalmology Trainee Clinical Trial Network (OCT...
PurposeThe aim of this analysis was to characterize the spectrum inflammatory changes arising from brolucizumab use in routine clinical practice.DesignRetrospective fluorescein angiography (FA), fundus photography (FP) and optical coherence tomography (OCT) images taken at time adverse event.SubjectsBrolucizumab-treated patients with neovascular age-related macular degeneration (nAMD) retinal v...
Multi-core accelerators offer significant potential to improve the performance of parallel applications. However, tools to help the parallel application developer understand accelerator performance and its impact are scarce. An approach is presented to measure the performance of GPU computations programmed using CUDA and integrate this information with application performance data captured with...
Figure 1: The first all-atom structure of the complete HIV virus capsid [1], a breakthrough enabled by CUDA technology in NAMD, VMD, and the Blue Waters supercomputer at Illinois. The first scientific breakthrough achieved with the Blue Waters supercomputer at the University of Illinois was the determination of the structure of the complete HIV capsid in atomic-level detail, a collaborative eff...
Schizophrenia is a complex, chronic mental disorder, affecting about 21 million people worldwide. It is characterized by symptoms, including distortions in thinking, perception, emotions, disorganized speech, sense of self and behavior. Recently, a numbers of marketed drugs for Schizophrenia are available against dopamine D2 and serotonin 5-HT2A receptors. Here, we docked Olanzapine derivatives...
Cryptosporidium parvum is the common enteric protozoan pathogen causing cryptosporidiosis in human. Available drugs to treat cryptosporidiosis are ineffective and there is yet no vaccine against C. parvum. Therefore, it is of interest to design an improved yet effective drug against C. parvum. Here, we docked benzoxazole derivatives (collected from literature) with inosine 5`- monophosphate deh...
Intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents are widely used to treat neovascular age-related macular degeneration (nAMD). Although these treatments are effective, multiple injections have recently been recommended to ensure that there is a good long-term prognosis. However, sustained intraocular pressure (IOP) elevations have been reported to develop after m...
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