BACKGROUND Salivary rinses have been recently proposed as a valuable resource for the development of epigenetic biomarkers for detection and monitoring of head and neck squamous cell carcinoma (HNSCC). Both salivary rinses collected with and without an exfoliating brush from patients with HNSCC are used in detection of promoter hypermethylation, yet their correlation of promoter hypermethylatio...

A long cherished dream of both scientists and artists since the birth of digital computers is to be able to use the computer to produce beautiful art. With the ever increasing power of modern computers, the computer as a serious artistic tool is now within reach for many. One major research area in computer art is emulating traditional art media for interactive painting or calligraphy. A brush ...

The 'missing peptidase' hypothesis to explain the aetiology of coeliac disease has never been satisfactorily resolved and recent reports suggest that coeliac brush borders may have depressed levels of specific peptidase enzymes. It has been inferred from these studies that the subsequent brush border digestion of gliadin peptides may therefore be defective. In this present study a sensitive flu...

We use Brownian dynamics simulations to study the adsorption behavior of a nanosized particle on polymer brushes. The adsorption process, the dynamic behavior of the nanoparticle in brush, the penetration depth, and the di usion coe cient of the nanoparticle in di erent depths of the brush are all investigated for di erent grafting densities. We provide an area density Γ , which is the area ave...

We present CoolPaint, a system for computer painting that uses a props-based direct interaction technique. By instrumenting real paint brushes and developing corresponding digital models of the brushes, we allow the user to control digital tools by directly manipulating their physical counterparts. In addition, we use a tabletop display which allows the display space and interaction space to be...

Cationic amphiphilic diblock copolymers were synthesized by RAFT polymerization and the nanostructure of their monolayers was investigated by π-A isotherm and X-ray reflectivity. Carpet layer (dense hydrophilic block layer) formation under the hydrophobic layer was confirmed and a “brush” layer was found beneath the carpet layer. However, the thickness of brush layer was much thinner than that ...

Government regulations to address technological risks are important for the successful development and application of nanotechnology, but there is an ongoing debate in the USA about who is responsible for the regulation of nanotechnology. In a mail survey of leading US nano-scientists, we examine scientists’ perceptions about nano-regulation, including the government level (local, national, or ...

The interactions between spherical colloids covered with end-grafted polymers (brushes) immersed in a polymer melt are studied theoretically. We show that attractive enthalpic interactions between the two polymer species, characterized by a negative Flory parameter (chi<0), can stabilize the colloidal dispersion. The stabilizing mechanism is a result of a structural change from a dry brush, whe...