Nanomaterials are increasingly used as drug carriers for cancer therapy. Nanomaterials also appeal to researchers in the areas of cancer diagnosis and biomarker discovery. Several antitumor nanodrugs are currently being tested in preclinical and clinical trials and show promise in therapeutic and other settings. We review the development of nanomaterial drug carriers, including liposomes, polym...

Boron neutron capture therapy (BNCT) is an effective clinical method in cancer treatment based on fission reactions and nuclear capturing. In this method, use of the best boron-containing agents for boron therapy and boron delivery agent for transfer to the infectious site are the key points for  efficienct treatment. Our research indicated that calcium fructoborate(CF) was the best compound as...

In order to obtain antineoplastic compounds and innovative formulations, new technologies testing methods are continuously being developed. Unfortunately, besides cancer cells, chemotherapy also affects normal cells. An option avoid toxicity is represented by the targeted treatment using novel pharmaceutical dosage forms.
 Liposomes represent a relatively form, used for their many advantag...

Intranasal vaccination is particularly a striking route for mucosal immunization, due to the ease of administration and the induction of both mucosal and humoral immunity. However, soluble antigens (Ag) are not sufficiently taken up after the nasal administration and need to be co-administered with adjuvants, penetration enhancers or encapsulated in particles. So, in this study, tetanus toxoid ...

The presence of heparin in a biological environment affects the cellular uptake extent positively charged liposomes but not negatively liposomes.

the current methods for treatment of cancers are inadequate and more specific methods such as gene therapy are in progress. among different vehicles, cationic liposomes are frequently used for delivery of genetic material. this investigation aims to prepare and optimize dotap cationic liposomes containing an antisense oligonuclotide (asodn) against protein kinase c alpha in non-small cells lung...

Drug delivered can have significant effect on its efficacy. Some drugs have an optimum concentration range with in which maximum benefit is derived and concentrations above (or) below the range can be toxic or produce no therapeutic effect. Various drug delivery and drug targeting systems are currently under development. The main goal for developing such delivery systems is to minimize drug deg...

Liposomes have attracted great interest as efficient carriers for nutrients, drugs and other bioactive agents as well as ideal models for biological membranes. This article intends to provide an overview of liposomes and nanoliposomes definition as well as their properties and preparation methods. Also it elaborates on various applications of nanoliposomes in nanotherapy including diagnostics, ...

Une nouvelle classe de transporteurs médicaments fabriqués avec l’ADN, qui pourrait améliorer façon importante le traitement des cancers et d’autres maladies, a été conçue validée par une équipe chercheur l’université Montréal. Contrairement aux nano-véhicules artificiels actuels (liposomes…), où la concentration médicament libéré dans temps ces véhicules peut varier grandement d’un patient à l...