The aim of this study was to investigate the characteristic red palm oil nanostructured lipid carriers (RPO-NLC) made with microemulsion method. procedures prepared ratio Tween 80 : Span 20 (80:20 ; 70:30), surfactant (1:3.75 1:4), stearin (8:2 7:3 6:4). best particle size found at 80:20, 1:4, 6:4 respectively 24.73 ± 0.06 nm, zeta potential -7.43, turbidity 0,183% and polydispersity index 0.06...

BACKGROUND AND THE PURPOSE OF THE STUDY Domperidone (DOM) is a dopamine- receptor (D(2)) antagonist, widely used in the treatment of motion-sickness. The pharmacokinetic parameters of DOM make it a suitable candidate for development of Solid Lipid Nanoparticle (SLN) and Nanostructured Lipide Carrier (NLC). The purpose of the present investigation was to prepare and evaluate DOM loaded solid lip...

The present study investigated the characteristics of diclofenac diethylammonium-containing NLC as function ratio glyceryl monostearate (GMS) and caprylic acid (mygliol 80) 65:35; 75:25 85:15. There were three formulas composition each formula diethylammonium 1.16%; with (65:35; 85:15); Tween 80 5%; phosphate buffer pH 6.0 ± 0.1 dispersion medium. result showed that had different characteristic...

Sea buckthorn (SB) (Elaeagnus rhamnoides (L.) A. Nelson) is rich in flavonoids, phenolic compounds, anthocyanins, carotenoids, and phytosterol. Its phytochemicals exhibit various biological activities, such as antioxidant, immunomodulatory anti-carcinogenic activities. SB also helps prevent the development of wrinkles protects skin’s surface from UV rays. The purpose present study was to develo...

Propofol (2,6-diisopropylphenol), being used as an intravenous sedative and anesthetic agent, influences not only upon nervous system but also for host inflammatory response through modulating neutrophil functions. This study is designed to evaluate the modulating effects of propofol and its lipid carrier administration at clinically relevant rate on canine neutrophil functions. Clinically heal...