nasal obstruction) were recorded before challenge and every 15 minutes after challenge initiation. For the evaluation of nasal obstruction, we used visual analog scales (VASs); subjects marked a site on a 10-cm line corresponding to the symptom severity on which absence of symptoms was designated as 0 and worst imaginable symptom as 10. PIFR was measured using an In-check flow meter and nasal r...

nasal obstruction) were recorded before challenge and every 15 minutes after challenge initiation. For the evaluation of nasal obstruction, we used visual analog scales (VASs); subjects marked a site on a 10-cm line corresponding to the symptom severity on which absence of symptoms was designated as 0 and worst imaginable symptom as 10. PIFR was measured using an In-check flow meter and nasal r...

On histopathological examination, nasal polyps and nasal mucosa in allergic rhinitis show different forms of pseudostratified respiratory epithelium, whereas the dominant characteristic of lamina propria is an eosinophilic infiltration. The aim of this study was to compare interleukin (IL)-5 and eosinophilic cationic protein (ECP) levels in the nasal fluid of 42 patients: 12 with allergic rhini...

In diseases such as bronchial asthma or atopic dermatitis, which are based on a type II inflammation, biologicals part of the standard therapy. Since October 2019, bilogical dupilumab has been approved an add-on therapy for treatment severe chronic rhinosinusitis with nasal polyposis (CRSwNP). The aim this study is to evaluate acceptability, symptom development, and side effects after one year ...

PURPOSE Nasal polyposis is a chronic inflammatory disease of the upper airways often associated with asthma and characterized by markedly increased numbers of eosinophils, Th2 type lymphocytes, fibroblasts, goblet cells and mast cells. Previous studies have shown elevated levels of thymic stromal lymphopoietin (TSLP) in atopic diseases like asthma, atopic dermatitis and mainly in animal models ...

OBJECTIVES We assessed the efficacy of different forms of fluticasone propionate in the treatment of bilateral nasal polyposis in adult patients. PATIENTS AND METHODS This double-blind, randomized, parallel group study included 34 patients, aged 16 years or over, with a diagnosis of bilateral nasal polyposis. The patients were randomized to three groups to receive fluticasone propionate in th...

Nasal Polyposis (N.P) is not simply mucosa oedema, but rather grape shaped, smooth, soft, freely mobile mucosal swellings that are often visible on anterior rhinoscopy. Polyps arise from the lateral wall of nose. N.P. may be present without clinically significant sinus disease and vice versa. In Ayurveda, polyposis can understood with Nasa Arsha. Modern management includes antibiotic, systemic ...

BACKGROUND The waiting time for functional endoscopic sinus surgery (FESS) in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) in the Canadian public healthcare system can be lengthy. Many such patients have significant nasal obstruction resulting in a poor quality of life. A simple and safe office-based polypectomy device to debulk nasal polyps allows immediate alleviation of...