Individuals with Parkinson's disease (PD) often suffer from comorbid depression. P11 (S100A10), a member of the S100 family of proteins, is expressed widely throughout the body and is involved in major depressive disorder and antidepressant response. Central p11 levels are reduced in postmortem tissue from depressed individuals; however, p11 has not yet been investigated in PD patients with dep...

In natural populations, the expression and severity of inbreeding depression can vary widely across taxa. Describing processes that influence the extent of inbreeding and inbreeding depression aid in our understanding of the evolutionary history of mating systems such as cooperative breeding and nonrandom mate selection. Such findings also help shape wildlife conservation theory because inbreed...

Inbreeding, which is common in plants, may increase the vulnerability of populations to natural enemies. Similarly, natural enemies may increase the expression of inbreeding depression in their hosts, resulting in altered selection on host mating-system evolution. To examine effects of inbreeding on tolerance to herbivory, we transplanted experimentally selfand cross-fertilized plants into four...

Background and Purpose—The longer-term natural history of depression after stroke is poorly understood. We estimate frequency, predictors, and associations of depression up to 5 years after stroke in a population-based study. Methods—Data from 3689 patients registered in the South London Stroke Register 1995 to 2006 were used. Baseline data included age, sex, ethnicity, socioeconomic status, an...

BACKGROUND AND PURPOSE The longer-term natural history of depression after stroke is poorly understood. We estimate frequency, predictors, and associations of depression up to 5 years after stroke in a population-based study. METHODS Data from 3689 patients registered in the South London Stroke Register 1995 to 2006 were used. Baseline data included age, sex, ethnicity, socioeconomic status, ...

As part of a prospective study of mood disorders in stroke patients, interviews were obtained from 37 patients at 1 year and 48 patients at 2 years follow-up. In-hospital evaluations for these 65 follow-up patients found that 9 patients (14%) had symptom clusters of major depression, 12 patients (18%) had symptom clusters of dysthymic or minor depression, and 44 patients (68%) did not meet the ...

Recent decades have seen development of research and an increased interest in the psychopharmacology of natural remedies. More than 20 herbal remedies have been identified that may potentially be applied in medicine as antidepressive, anxiety relieving or sleep-inducing agents. Patients often prefer to take herbal remedies and often take them on their own, without consulting a physician. The ai...

Focusing on Xujiaweizi fault depression, the geological conditions and geochemical characteristics of deep natural gas formation in north Songliao basin are evaluated, resources estimated, favorable areas optimized. Shahezi Formation shale is a set coal bearing sediments with high organic matter abundance (TOC 1%～12%), over maturity (Ro 1%～4%) shore shallow lake facies, which mainly distributed...