In the last two decades, the survival rates of very low birth weight (VLBW) infants increased with the broad use of exogenous surfactant and new ventilation techniques. These preterm infants are one of the most vulnerable groups of patients for nosocomial infections (NIs) due to their immature immune system, necessary medical treatments, mechanical ventilation, and invasive procedures performed...

Background: Respiratory distress syndrome is one of the main complications associated with low birth weight, and a main cause of mortality in premature neonates. The present study aimed to compare the efficacy of ventilator continuous positive airway pressure (CPAP) and bubble CPAP in the treatment of respiratory distress syndrome (RDS) in premature neonates. Methods: This randomized controlled...

background: in patients undergoing mechanical ventilation, mucus production and secretion is high as a result of the endotracheal tube. because endotracheal suction in these patients is essential, chest physiotherapy techniques such as expiratory rib cage compression before endotracheal suctioning can be used as a means to facilitate mobilizing and removing airway secretion and improving alveol...

there is no randomized study carried out in order to compare their pharmacokinetic parameters although midazolam, as a sedative, has been widely administered via continuous infusion as well as intermittent bolus doses in mechanically ventilated critically ill patients. we prospectively investigated the effect of these two principal methods on pharmacokinetic parameters in 23 of mentioned patien...

objectives the aim of this study was to study the incremental cost-effectiveness ratio associated with the use of heat and moisture exchangers (hme) filter to prevent vap compared with the heated humidifiers (hh) presently adopted by intensive care unit (icu) services within the brazilian healthcare unified system. patients and methods this study was a cost-effectiveness analysis (cea) comparin...

Background Chest physiotherapy has been used to clear secretions in pediatrics for many respiratory problems. The aim of this study was to investigate the effect of chest physical therapy on full term neonates with primary pneumonia. Materials and Methods Sixty full term neonates admitted to  neonatal intensive care unit (NICU), Minia University, Egypt, during the period from September 2016 to...

background: application noninvasive ventilation in the patients with exacerbation of chronic obstructive pulmonary disease (copd) reduced mortality. this case-control study was designed to compare efficiency and outcome of non-invasive (niv) versus invasive positive pressure ventilation (ippv) in respiratory failure due to copd methods: the patients were assigned to niv or ippv intermittantly.t...

background endotracheal suctioning is a necessary procedure practiced by nurses in intensive care units to remove lung secretions. this procedure leads to higher oxygenation levels and reduced breathing difficulties. it also prevents atelectasis, pulmonary infections, and the accumulation of secretions. objectives the present study aims to compare the effectiveness of open and closed endotrache...

OBJECTIVE To discuss over NO inhalation (iNO) in combination with high frequency ventilation treatment in relieving clinical symptoms and respiratory state of patients with neonatal severe respiratory failure. METHODS Ninety newborns with severe respiratory failure who received treatment in our hospital were selected for this study. They were divided into research group and control group acco...

OBJECTIVE To review the use of airway pressure release ventilation (APRV) in the treatment of acute lung injury/acute respiratory distress syndrome. DATA SOURCE Published animal studies, human studies, and review articles of APRV. DATA SUMMARY APRV has been successfully used in neonatal, pediatric, and adult forms of respiratory failure. Experimental and clinical use of APRV has been shown ...