A rare case of a Wilms tumor with intracardiac neoplastic extension is presented. The good prognosis of even extensive nephroblastoma is the reason for attempting a radical surgical approach to patients with intracardiac tumor thrombus. The exact preoperative delineation of the intracasal tumor extension is essential for a safe and successful operation. Ultrasonography in combination with echoc...

The review article analyzes the data accumulated in literature on association of Wilms’ tumor with chromosomal syndromes and searches for possible causes this phenomenon. In 10 % all cases, nephroblastoma is represented by a hereditary syndrome due to germline mutations suppressor genes, mainly WT1 gene, less often WT2 , WTX CTNNB1 TP53 . These genes are associated retroelements that play role ...

Neuroblastoma (NBL) is the most common extra-cranial tumour in childhood. It can present as an abdominal mass, but is usually metastatic at diagnosis so the symptomatology can be varied. Nephroblastoma, also more commonly known as a Wilms tumour, is the commonest renal tumour in childhood and more typically presents as abdominal pathology with few constitutional symptoms, although rarely haemat...

INTRODUCTION Childhood cancer is relatively rare, but there is a very good chance of cure. While overall survival rates of >70% are reported from developed countries, survival is much less likely in developing countries and unknown in many countries in Africa. OBJECTIVE To analyse survival rates of childhood cancers in two South African paediatric oncology units. METHODS This retrospective ...

Mitchell, J. D., Baxter, Thelma J., Blair-West, J. R., and McCredie, D. A. (1970). Archives of Disease in Childhood, 45, 376. Renin levels in nephroblastoma (Wilms' tumour). Report of a renin secreting tumour. The case history is reported of a child aged 1 year 10 months with malignant hypertension in association with Wilms' tumour. In addition there was a marked electrolyte disturbance, with h...

Nephroblastoma – also known as Wilms tumor – is the most frequent renal malignancy in childhood with the highest incidence of this tumor within the fourth year of life. 80% of patients are less than 5 years old, however it is a rare condition in neonates (<1%). In general, there are no known risk factors for the development of nephroblastoma, but it may be associated with rare conditions like D...