نتایج جستجو برای: nested polymerase chain reaction nested

تعداد نتایج: 707924  

Journal: :Journal of forensic sciences 2008
Hiroaki Nakahara Kazumasa Sekiguchi Kazuhiko Imaizumi Natsuko Mizuno Kentaro Kasai

When mitochondrial DNA (mtDNA) heteroplasmies are detected, they often confound forensic identification, especially if they are the result of poor biological sampling. In this study, we determined the ratio of heteroplasmy in samples that were amplified from a very small amount of template mtDNA or a few cells using a highly sensitive nested polymerase chain reaction (PCR) procedure and a direc...

2018
Sho KADEKARU Yumi UNE

We previously reported that the tadpole of bullfrog (Lithobates catesbeiana) is a useful model for the field surveillance of the Batrachochytrium dendrobatidis (Bd) distribution. In the present study, we compared Bd detection rates in swab-scraped and resected mouthpart samples, using nested polymerase chain reaction (PCR). The resulting detection rates for swab-scraped and resected specimens w...

2017
Inke N. D. Lubis Hendri Wijaya Munar Lubis Chairuddin P. Lubis Paul C. S. Divis Khalid B. Beshir Colin J. Sutherland

Background As Indonesia works toward the goal of malaria elimination, information is lacking on malaria epidemiology from some western provinces. As a basis for studies of antimalarial efficacy, we set out to survey parasite carriage in 3 communities in North Sumatera Province. Methods A combination of active and passive detection of infection was carried out among communities in Batubara, La...

Journal: :Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 1999
H Rinder K Feldmann E Tortoli J Grosset M Casal E Richter M Rifai V Jarlier M Vaquero S Rüsch-Gerdes E Cambau J Gutierrez T Löscher

BACKGROUND The molecular prediction of isoniazid (INH) resistance in Mycobacterium tuberculosis is hampered by the need for specialized equipment, expertise, high costs, a limited range of detectable mutations, or several of these factors. The rationale for the study was to find a practical alternative and to demonstrate generally valid problems. METHODS AND RESULTS DNA extracted from deconta...

Journal: :Emerging Infectious Diseases 2001
D. J. Johnson E. N. Ostlund D. D. Pedersen B. J. Schmitt

A traditional single-stage reverse transcription-polymerase chain reaction (RT-PCR) procedure is effective in determining West Nile (WN) virus in avian tissue and infected cell cultures. However, the procedure lacks the sensitivity to detect WN virus in equine tissue. We describe an RT-nested PCR (RT-nPCR) procedure that identifies the North American strain of WN virus directly in equine and av...

Journal: :BMC Infectious Diseases 2004
Michael Schmid Rainer Oehme Gunnar Schalasta Stefan Brockmann Peter Kimmig Gisela Enders

BACKGROUND Noroviruses (NoV) have become one of the most commonly reported causative agents of large outbreaks of non-bacterial acute gastroenteritis worldwide as well as sporadic gastroenteritis in the community. Currently, reverse transcriptase polymerase chain reaction (RT-PCR) assays have been implemented in NoV diagnosis, but improvements that simplify and standardize sample preparation, a...

2017
Anita M. Shete Pragya Yadav Vimal Kumar Tushar Nikam Kurosh Mehershahi Prasad Kokate Deepak Patil Devendra T. Mourya

BACKGROUND & OBJECTIVES Bats are recognized as important reservoirs for emerging infectious disease and some unknown viral diseases. Two novel viruses, Malsoor virus (family Bunyaviridae, genus, Phlebovirus) and a novel adenovirus (AdV) (family, Adenoviridae genus, Mastadenovirus), were identified from Rousettus bats in the Maharashtra State of India. This study was done to develop and optimize...

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