We report on a 60-year-old woman with neuroendocrine carcinoma of the left breast metastasizing to renal cell carcinoma (RCC) of the left kidney and to adrenal gland. A yellow, well-circumscribed tumor, 11 cm in largest diameter and limited to the kidney, was found. Histopathology revealed RCC with foci of neuroendocrine differentiation. Solid sheets of hyperchromatic epithelioid cells with hig...

Gastric neuroendocrine carcinomas are rare and have a poor prognosis, and the diagnostic criteria for this disease have recently changed. We herein report a case of sporadic gastric neuroendocrine carcinoma. A 75-year-old man was referred to our hospital with epigastric pain. Endoscopic examination revealed a localized ulcerative lesion (diameter, 4 cm) at the upper stomach. The diagnosis on bi...

We report a unique case of synchronous double primary gastric cancer consisting of adenocarcinoma components with micropapillary features and composite glandular-endocrine cell carcinoma components. The patient was a 53-year-old man presenting with a 6-month history of epigastric pain and diarrhea. A subtotal gastrectomy was performed. Histologically, one tumor was composed of micropapillary ca...

Neuroendocrine (NE) differentiation is infrequent in testicular tumors and its histogenesis is not well understood. The present study is aimed at elucidating the pathway of neuroendocrine differentiation in germ cell tumors (GCTs) of the testis. In the analysis of 46 germ cell tumor components from 23 testicular tumors, we focused on GCTs with neuroendocrine differentiation, 7 teratoma, 1 embry...

Context The selective arterial secretagogue injection test is a functional examination to determine localization of functional neuroendocrine tumor. Since the selective arterial secretagogue injection test capitalizes on the hormone-secreting ability of neuroendocrine tumor, no reports on this test in non-functional neuroendocrine tumors have yet been published. Objective In this study, we eval...

Endocrine disease related tumors of female reproductive system mostly seen in ovary. Hormone producing ovarian tumors, ovarian tumor with functioning stroma, tumor related paraneoplastic and paraendocrine syndromes, paraganglioma and neuroendocrine tumors may include in this category. These tumors or its stroma can produce some hormones, which are led to endocrine manifestations. Rarely tumors ...

S25 ENDOSCOPIC ULTRASOUND / VOLUME 6 / SUPPLEMENT 1 / AUGUST 2017 report was suggestive of neuroendocrine tumor, Grade 2. A DOTA scan was done for defining extent which revealed DOTA avid lesion in the right middle lung, mediastinal and abdominal lymph nodes, multiple liver space-occupying lesions, and bilateral bulky adrenal. He was finally diagnosed as lung neuroendocrine tumor with dissemina...

BACKGROUND Neuroendocine carcinoma of the gynecologic tract is rare and poses a significant clinical challenge because of tumor heterogeneity and lack of standardized guidelines for treatment. Ovotestis refers to the histology of a gonad that contains both ovarian follicles and testicular tubular elements. Ovotesticular disorder of sexual development occurs in fewer than 10% of all disorders of...

S25 ENDOSCOPIC ULTRASOUND / VOLUME 6 / SUPPLEMENT 1 / AUGUST 2017 report was suggestive of neuroendocrine tumor, Grade 2. A DOTA scan was done for defining extent which revealed DOTA avid lesion in the right middle lung, mediastinal and abdominal lymph nodes, multiple liver space-occupying lesions, and bilateral bulky adrenal. He was finally diagnosed as lung neuroendocrine tumor with dissemina...

Neuroendocrine differentiation (NED), which is not uncommon in prostate cancer, is increases in prostate cancer after androgen-deprivation therapy (ADT) and generally appears in castration-resistant prostate cancer (CRPC). Neuroendocrine cells, which are found in normal prostate tissue, are a small subset of cells and have unique function in regulating the growth of prostate cells. Prostate can...