نتایج جستجو برای: neurogenic differentiation
تعداد نتایج: 234643 فیلتر نتایج به سال:
how to cite this article: saeedi borujeni mj, esfandiary e, almasi dooghaee m. childhood neurogenic stuttering due to bilateral congenital abnormality in globus pallidus: a case report and review of the literature. iran j child neurol. autumn 2016; 10(4):75-79. abstract objective the basal ganglia are a group of structures that act as a cohesive functional unit. they are situated at the base ...
Human neocortex expansion likely contributed to the remarkable cognitive abilities of humans. This expansion is thought to primarily reflect differences in proliferation versus differentiation of neural progenitors during cortical development. Here, we have searched for such differences by analysing cerebral organoids from human and chimpanzees using immunohistofluorescence, live imaging, and s...
Since their beginning, morphological and functional studies of the mammalian central nervous system must deal with the complexity of the nervous tissue. Recent studies, by revealing the existence of neurogenesis throughout life, introduced a new aspect of complexity. Adult neurogenic sites are heterogeneous systems involving stem cell niches which contain actively dividing cells, migration rout...
The Sonic Hedgehog (Shh) signaling pathway is important for neurogenesis in vivo. Gli transcription factors, effector proteins of the Shh signaling pathway, have neurogenic properties in vivo, which are still poorly understood. To study the molecular basis of neurogenic properties of Gli2, we used a well-established embryonic stem cell model, the P19 embryonal carcinoma (EC) cell line, which ca...
Cerebellar GABAergic interneurons comprise heterogeneous phenotypes located at strategic levels of the local networks. Recent findings indicate that they all derive from a common population of multipotent progenitors whose fate choices are determined by instructive information provided by the PWM environment. Here we review about the atypical neurogenic strategy operated within such postnatal n...
A complete account of the whole developmental process of neurogenesis involves understanding a number of complex underlying molecular processes. Among them, those that govern the crucial transition from proliferative (self-replicating) to neurogenic neural progenitor (NP) cells remain largely unknown. Due to its sequential rostro-caudal gradients of proliferation and neurogenesis, the prospecti...
Background Glehnia littoralis has been used for traditional Asian medicine, which has diverse therapeutic activities. However, studies regarding neurogenic effects of G. littoralis have not yet been considered. Therefore, in this study, we examined effects of G. littoralis extract on cell proliferation, neuroblast differentiation, and the maturation of newborn neurons in the hippocampus of adul...
The development of the nervous system requires a strict control of cell cycle entry and withdrawal. The olfactory epithelium (OE) is noticeable by its ability to yield new neurons not only during development but also continuously during adulthood. The aim of our study was to investigate, by biochemical and immunohistochemical methods, which cell cycle regulators are involved in the control of n...
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