La pandemia de COVID-19 que comenzó en China se ha expandido rápidamente para afectar a todo el mundo cuestión meses. Las manifestaciones principales incluyen un síndrome febril acompañado síntomas respiratorios; sin embargo, cada vez reportan más casos afección sistémica, incluyendo la cardiaca y del sistema nervioso central.

OBJECTIVE To compare tetrathiomolybdate and trientine in treating patients with the neurologic presentation of Wilson disease for the frequency of neurologic worsening, adverse effects, and degree of neurologic recovery. DESIGN A randomized, double-blind, controlled, 2-arm study of 48 patients with the neurologic presentation of Wilson disease. Patients either received 500 mg of trientine hyd...

Nearly 70 years after the discovery of penicillin, neurologic infectious diseases (NIDs) remain an important worldwide source of morbidity and mortality. The clinician faced with a potential NID must urgently consider patient demographics, pace of illness and clinical syndrome, and laboratory data. In keeping with the topics of this issue, initial emergency diagnosis and management are emphasiz...

By Gustavo C Roman MD (Dr. Roman, Director of the Alzheimer Center of Excellence at the Methodist Neurological Institute in Houston, Texas, has no relevant financial relationships to disclose.) Pedro J Ruiz MD (Dr. Ruiz of the California Pacific Medical Center in San Francisco, California, has no relevant financial relationships to disclose.) Originally released June 28, 2006; last updated June...

Aphasia refers to a disorder of language processing caused by a dysfunction in specific brain regions. It is common after stroke and associated with relevant disability and higher mortality. Evaluation of language function (spontaneous speech, auditory comprehension, naming, repetition, reading and writing), allows classification of aphasia. Most patients present some degree of recovery. Speech...