Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome accompanied by isolated neurologic manifestations have been reported in children; however, Down ...

LLOWING the introduction of liver therapy for pernicious anemia in I9L6’ the curability of the neurologic manifestations of this disease became a matter of intense interest and large series of patients with acute, chronic and residual neurologic defects were treated with lightly cooked liver and oral liver extracts. It was found that while this treatment restored satisfactory blood levels and r...