Despite recent advances in acute stroke management, many stroke patients suffer from long-term disability. Most stroke patients regain their function partially or fully during the first 3 to 6 months depending on many factors ; pre-stroke, stroke and post-stroke factors. Brain plasticity plays a major role during stroke recovery, and motor-relearning and brain plasticity shares the common mecha...

Rosanna De Meo, Micah M. Murray, Stephanie Clarke and Pawel J. Matusz* 1 Neuropsychology and Neurorehabilitation Service, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland 2 Electroencephalography Brain Mapping Core, Center for Biomedical Imaging (CIBM), Lausanne and Geneva, Switzerland 3 The Laboratory for Investigative Neurophysiology, Neuropsychology ...

The brain is constantly adapting to environmental and endogenous changes (including injury) that occur at every stage of life. The mechanisms that regulate neural plasticity have been refined over millions of years. Motivation and sensory experience directly shape the rewiring that makes learning and neurological recovery possible. Guiding neural reorganization in a manner that facilitates reco...

Neurorehabilitation is at a crossroads. Indeed, there is inconclusive, but promising evidence about clinical effectiveness of rehabilitation in the field of neurological impairments. Translating the new theories on motor control into clinical research may help to develop new treatment strategies and guide rehabilitation approaches. The concepts of synergy and the uncontrolled manifold hypothesi...

Among the outstanding features of the blood picture in experimental syphilis of the rabbit, Pearce (1) has reported the following: A slight increase in the total white count; unchanged or lowered lymphocyte values during the earlier phase of the disease, with increased values during the period of regression and healing of lesions; and a marked increase in the number of monocytes during the peri...

OBJECTIVE To systematically review how process evaluations are currently designed, what methodologies are used and how are they developed alongside or within neurological rehabilitation trials. METHODS This mixed-methods systematic review had two evidence streams: stream I, studies reporting process evaluations alongside neurorehabilitation trials research and stream II, methodological guidan...

Most people choose to listen to music that they prefer or 'like' such as classical, country or rock. Previous research has focused on how different characteristics of music (i.e., classical versus country) affect the brain. Yet, when listening to preferred music--regardless of the type--people report they often experience personal thoughts and memories. To date, understanding how this occurs in...

INTRODUCTION Neurological soft signs (NSS) are suggested as a candidate endophenotype for schizophrenia. This article aims to review relevant literature and discuss the role of NSS in understanding schizophrenia. METHODS This is an update on a review article published in 2003. Articles from 2003 onwards were specifically reviewed and discussed with relevance to the role of NSS as endophenotyp...

Alexander Morenoa,b,∗, Caron Ganc and Nathan D. Zaslerd aFaculty of Human Sciences, Department of Sexology, Université du Québec à Montréal (UQÀM), Canada bCenter for Interdisciplinary Research in Rehabilitation of Greater Montreal, Canada cBloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, Canada dConcussion Care Centre of Virginia, Ltd. and Tree of Life...

The Centennial Vision articulated by the American Occupational Therapy Association includes moving the profession to being science driven and evidence based. The American Journal of Occupational Therapy contributes to this vision by publishing high-quality research. I reviewed research in the practice area of neurological rehabilitation published between May 2010 and October 2011. In particular...